Type | Description |
---|---|
Definition | outer dense fiber of sperm tails 1 |
Date | Results | Publications |
---|---|---|
2018-07-21 10:47:00 | Thiols of flagellar proteins, such as outer dense fibre protein 1 (ODF1), are oxidised to form disulfides during epididymal transit and the spermatozoa become motile. This study was designed to determine how oxidative changes in protein thiol status affect progressive motility in spermatozoa. | 27363428 |
2017-06-10 11:41:00 | Study provides evidence that ODF1 down regulation is responsible for male infertility. | 27770032 |
2010-06-30 22:06:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
2010-05-10 11:08:00 | The expression of ODF1 was significantly decreased in the ejaculated spermatozoa of asthenozoospermic men. | 20112736 |
Type | IDs |
---|---|
Synonymous | CT133, HSPB10, ODF, ODF2, ODF27, ODFP, ODFPG, ODFPGA, ODFPGB, RT7, SODF |
Gene |
UniProtKB-ID:
ODFP1_HUMAN
UniprotKB:
Q14990
UniParc:
UPI000013DDEA
EMBL:
X74614,
BC104457,
BC104456,
M93131
Ensembl:
ENSG00000155087
KO:
hsa:4956
|
Nucleutide sequences |
EMBL-CDS:
CAA52685.1,
AAI04457.1,
AAI04458.1
Ensembl_TRS:
ENST00000285402
|
Protein sequencees |
Ensembl_PRO:
ENSP00000285402
RefSeq:
NP_077721.2
|
Others |
UniRef100:
UniRef100_Q14990
UniRef90:
UniRef90_Q14990
UniRef50:
UniRef50_Q14990
UniGene:
Hs.159274
CCDS:
CCDS6293.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
31515488 |
Nat Commun Robert Fragoza , Jishnu Das , Shayne D Wierbowski , Jin Liang , Tina N Tran , Siqi Liang , Juan F Beltran , Christen A Rivera-Erick , Kaixiong Ye , Ting-Yi Wang , Li Yao , Matthew Mort , Peter D Stenson , David N Cooper , Xiaomu Wei , Alon Keinan , John C Schimenti , Andrew G Clark , Haiyuan Yu |
2019-09-12 | - |
27363428 |
Thiols of flagellar proteins are essential for progressive motility in human spermatozoa. Reprod. Fertil. Dev. MarÃa Eugenia Cabrillana , MarÃa de Los Ãngeles Monclus , Tania Estefania Sáez Lancellotti , Paola Vanina Boarelli , Amanda Edith Vincenti , Miguel Matias Fornés , Eduardo Alfredo Sanabria , Miguel Walter Fornés |
2017-07-01 | - |
28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
27770032 |
Deficiency in Outer Dense Fiber 1 Is a Marker and Potential Driver of Idiopathic Male Infertility. Mol Cell Proteomics Louise Hetherington , Elena K Schneider , Caroline Scott , David DeKretser , Charles H Muller , Hubert Hondermarck , Tony Velkov , Mark A Baker |
2016-12-01 | - |
25416956 |
A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal |
2014-11-20 | - |
23770605 |
Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. Nat. Genet. Sonja I Berndt , Christine F Skibola , Vijai Joseph , Nicola J Camp , Alexandra Nieters , Zhaoming Wang , Wendy Cozen , Alain Monnereau , Sophia S Wang , Rachel S Kelly , Qing Lan , Lauren R Teras , Nilanjan Chatterjee , Charles C Chung , Meredith Yeager , Angela R Brooks-Wilson , Patricia Hartge , Mark P Purdue , Brenda M Birmann , Bruce K Armstrong , Pierluigi Cocco , Yawei Zhang , Gianluca Severi , Anne Zeleniuch-Jacquotte , Charles Lawrence , Laurie Burdette , Jeffrey Yuenger , Amy Hutchinson , Kevin B Jacobs , Timothy G Call , Tait D Shanafelt , Anne J Novak , Neil E Kay , Mark Liebow , Alice H Wang , Karin E Smedby , Hans-Olov Adami , Mads Melbye , Bengt Glimelius , Ellen T Chang , Martha Glenn , Karen Curtin , Lisa A Cannon-Albright , Brandt Jones , W Ryan Diver , Brian K Link , George J Weiner , Lucia Conde , Paige M Bracci , Jacques Riby , Elizabeth A Holly , Martyn T Smith , Rebecca D Jackson , Lesley F Tinker , Yolanda Benavente , Nikolaus Becker , Paolo Boffetta , Paul Brennan , Lenka Foretova , Marc Maynadie , James McKay , Anthony Staines , Kari G Rabe , Sara J Achenbach , Celine M Vachon , Lynn R Goldin , Sara S Strom , Mark C Lanasa , Logan G Spector , Jose F Leis , Julie M Cunningham , J Brice Weinberg , Vicki A Morrison , Neil E Caporaso , Aaron D Norman , Martha S Linet , Anneclaire J De Roos , Lindsay M Morton , Richard K Severson , Elio Riboli , Paolo Vineis , Rudolph Kaaks , Dimitrios Trichopoulos , Giovanna Masala , Elisabete Weiderpass , MarÃa-Dolores Chirlaque , Roel C H Vermeulen , Ruth C Travis , Graham G Giles , Demetrius Albanes , Jarmo Virtamo , Stephanie Weinstein , Jacqueline Clavel , Tongzhang Zheng , Theodore R Holford , Kenneth Offit , Andrew Zelenetz , Robert J Klein , John J Spinelli , Kimberly A Bertrand , Francine Laden , Edward Giovannucci , Peter Kraft , Anne Kricker , Jenny Turner , Claire M Vajdic , Maria Grazia Ennas , Giovanni M Ferri , Lucia Miligi , Liming Liang , Joshua Sampson , Simon Crouch , Ju-Hyun Park , Kari E North , Angela Cox , John A Snowden , Josh Wright , Angel Carracedo , Carlos Lopez-Otin , Silvia Bea , Itziar Salaverria , David Martin-Garcia , Elias Campo , Joseph F Fraumeni , Silvia de Sanjose , Henrik Hjalgrim , James R Cerhan , Stephen J Chanock , Nathaniel Rothman , Susan L Slager |
2013-08-01 |
BCL2L11,
TSPAN32,
CDKN2B,
SP140,
IRF8,
SP110,
FAS,
IRF4,
MYC,
ODF1,
LEF1,
PMAIP1,
ACOXL,
MNS1,
SCN3B,
PTGDR,
GRAMD1B,
BAK1,
ACTA2,
BCL2,
RPLP1,
RFX7,
KLF10,
CASP8,
CASP10,
FARP2
|
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
21630459 |
Proteomic characterization of the human sperm nucleus. Proteomics Sara de Mateo , Judit Castillo , Josep Maria Estanyol , José Luis Ballescà , Rafael Oliva |
2011-07-01 |
DNAJB6,
GPC6,
PSME3,
PSMD14,
KATNB1,
TUBB3,
TUBB4A,
TUBB4B,
PRDX4,
AKAP3,
CENPA,
C6orf10,
PTGES3,
ACTL7A,
TOMM34,
RCC1,
ZPBP,
NUDT5,
TUBA3E,
PARK7,
IZUMO4,
PHB2,
TUBA3D,
PTPMT1,
HIST4H4,
C16orf78,
ZPBP2,
HIST2H3C,
TMCO2,
HMGB4,
HIST3H2BB,
LYZL4,
NUDT16,
GNPDA2,
EVC2,
PACRG,
PRSS37,
DYNLL2,
RPL10L,
BANF2,
CS,
PSMA8,
SLC2A14,
CSNK2A1,
CSNK2A2,
CSNK2B,
TEKT5,
SLC25A10,
TMEM190,
FAM71A,
TEKT4,
CTSG,
FAM81B,
CYC1,
FAM71B,
CYLC1,
CYLC2,
EEF1A1P5,
DNAJB8,
DECR1,
CRISP1,
DGUOK,
DLST,
DSP,
EEF1A1,
EEF1D,
EEF1G,
EEF2,
FAM209A,
ENO1,
TUBB,
CT83,
ALAD,
ALB,
ARMC12,
HIST1H2AA,
GPC4,
ALDOA,
FLG,
PSME4,
DNAJC9,
SYNE1,
SUZ12,
RPL13A,
DNPEP,
GTPBP4,
TSSK2,
MTCH2,
FTH1,
HIST1H2BA,
MPC2,
DPCD,
FAM205A,
NIPSNAP3A,
GAPDH,
TKFC,
TES,
RIBC2,
CABYR
|
21597245 |
Tohoku J. Exp. Med. Yanyan Liu , Min Jiang , Chao Li , Ping Yang , Huaqin Sun , Dachang Tao , Sizhong Zhang , Yongxin Ma |
2011-06-01 | - |
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