| Type | Description |
|---|---|
| Definition | ATG5 autophagy related 5 homolog (S. cerevisiae) |
| Date | Results | Publications |
|---|---|---|
| 2017-11-26 00:37:00 | Data suggest that atg5 expression level in dopaminergic (DA) neurons is decreased and autophagy flux is blocked in zebrafish MPTP model of Parkinson's disease (PD); gene therapy in embryo/larva resulting in human ATG5 overexpression reverses PD pathological features, rescues DA neurons, and restores autophagy flux in DA neurons; thus, ATG5 plays role in neuroprotection. | 28928221 |
| 2012-06-23 10:06:00 | The important role of atg5 gene in zebrafish neurogenesis and organogenesis, is reported. | 22082871 |
| Type | IDs |
|---|---|
| Synonymous | apg5l, zgc:100934 |
| Gene |
UniProtKB-ID:
F1RDC0_DANRE
UniprotKB:
F1RDC0
UniParc:
UPI000024B59E
EMBL:
AL928573
Ensembl:
ENSDARG00000023396
KO:
dre:494180
|
| Nucleutide sequences |
Ensembl_TRS:
ENSDART00000149086,
ENSDART00000029727
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000124077,
ENSDARP00000030870
RefSeq:
NP_001009914.2,
NP_991181.2
|
| Others |
UniRef100:
UniRef100_F1RDC0
UniRef90:
UniRef90_Q6TH46
UniRef50:
UniRef50_Q6TH46
UniGene:
Dr.12686
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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