| Type | Description |
|---|---|
| Definition | cytochrome P450 family 1 subfamily A member 2 |
| Date | Results | Publications |
|---|---|---|
| 2012-05-19 11:44:00 | Data suggest that CYP1A2 is significant enzyme responsible for formation of acetaminophen from phenacetin; however, it is not likely to be only enzyme or pathway responsible for the elimination of phenacetin or in vivo generation of acetaminophen. | 22074769 |
| 2011-08-13 11:36:00 | a total of 508 dogs from 38 different breeds were genotyped for the CYP1A2 1117C > T polymorphism | 21219354 |
| 2010-01-21 00:00:00 | canine CYP1A2 1117 C > T SNP causes protein deletion | 15742977 |
| 2010-01-21 00:00:00 | A single nucleotide polymorphism in the dog CYP1A2 gene causes these animals to be CYP1A2 deficient (i.e., lack functional CYP1A2 enzyme activity). Genotyping a colony of 79 dogs revealed 77% wild-type, 19% heterozygous, and 4% homozygous mutant animals | 19356037 |
| 2010-01-21 00:00:00 | There is the interindividual variability between the pharmacokinetic profiles of the YM-64227 with respect to the CYP1A2 deficiency polymorphism. | 16882764 |
| Type | IDs |
|---|---|
| Synonymous | CYPIA2, DAH2 |
| Gene |
UniProtKB-ID:
Q5R2U2_CANLF
UniprotKB:
Q5R2U2
UniParc:
UPI000049541F
EMBL:
AB094347
KO:
cfa:494010
|
| Nucleutide sequences |
EMBL-CDS:
BAD74212.1
|
| Protein sequencees |
RefSeq:
NP_001008720.1,
XP_013964818.1
|
| Others |
UniRef100:
UniRef100_Q5R2U2
UniRef90:
UniRef90_P56592
UniRef50:
UniRef50_P00185
UniGene:
Cfa.14521
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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