| Type | Description |
|---|---|
| Definition | glutathione peroxidase 8 (putative) |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:27:00 | Characterization of the endoplasmic reticulum-resident peroxidases GPx7 and GPx8 shows the higher oxidative activity of GPx7 and its linkage to oxidative protein folding. | 32719007 |
| 2021-02-02 13:25:00 | Glutathione Peroxidase 8 as a Prognostic Biomarker of Gastric Cancer: An Analysis of The Cancer Genome Atlas (TCGA) Data. | 32392186 |
| 2020-10-24 14:11:00 | The glutathione peroxidase 8 axis is essential in maintaining an aggressive breast cancer phenotype. | 32817494 |
| 2018-03-10 10:46:00 | Study provides evidence that the conserved N-terminal transmembrane domain of GPX8, in addition to its enzymatic activity, is essential for regulating Ca(2+) dynamics revealing a novel level of integration between redox-related proteins and Ca(2+) signaling/homeostasis. | 28129698 |
| 2015-12-05 11:40:00 | GPX8 is transcriptionally regulated by HIFalpha and modulates growth factor signaling in HeLa cells. | 25557012 |
| Type | IDs |
|---|---|
| Synonymous | EPLA847, GPx-8, GSHPx-8, UNQ847 |
| Gene |
UniProtKB-ID:
GPX8_HUMAN,
B4DPY0_HUMAN,
E7ETY7_HUMAN,
J3KNB5_HUMAN
UniprotKB:
Q8TED1,
B4DPY0,
E7ETY7,
J3KNB5
UniParc:
UPI000020C75B,
UPI0000E20923,
UPI00005A91DD,
UPI000013E37B
EMBL:
BC029424,
CH471123,
AK074216,
AK298545,
AC091977,
AY358715
Ensembl:
ENSG00000164294
KO:
hsa:493869
|
| Nucleutide sequences |
EMBL-CDS:
AAH29424.1,
AAQ89077.1,
BAB85019.1,
EAW54908.1,
BAG60742.1
Gene_ORFName:
UNQ847/PRO1785
Ensembl_TRS:
ENST00000503787,
ENST00000515370,
ENST00000296734
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000423822,
ENSP00000427466,
ENSP00000296734
RefSeq:
NP_001293127.1,
NP_001008398.2,
XP_006714694.1,
NP_001293126.1,
NP_001293130.1
|
| Others |
UniRef100:
UniRef100_J3KNB5,
UniRef100_B4DPY0,
UniRef100_E7ETY7,
UniRef100_Q8TED1
UniRef90:
UniRef90_J3KNB5,
UniRef90_Q8TED1,
UniRef90_F1SLM7
UniRef50:
UniRef50_J3KNB5,
UniRef50_F6TRR3,
UniRef50_Q8TED1
UniGene:
Hs.289044
CCDS:
CCDS34156.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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