| Type | Description |
|---|---|
| Definition | nuclear VCP like |
| Date | Results | Publications |
|---|---|---|
| 2020-01-04 12:06:00 | Data show that the nuclear exosome adaptors nuclear valosin-containing protein-like (NVL) and zinc finger, CCHC domain containing 8 protein (ZCCHC8) bind the Mtr4 exosome RNA helicase (MTR4) KOW domain on a surface. | 31358741 |
| 2018-01-20 10:27:00 | knockdown of WDR74 leads to significant defects in the pre-rRNA cleavage within the internal transcribed spacer 1, occurring in an early stage of the processing pathway. When the dissociation of WDR74 from the MTR4-containing exonuclease complex was impaired upon expression of mutant NVL2, the same processing defect, with partial migration of WDR74 from the nucleolus towards the nucleoplasm, was observed. | 29107693 |
| 2016-03-05 11:03:00 | Results indicated that the NVL gene may contain overlapping common genetic risk factors for major depressive disorder and schizophrenia in the Han Chinese population | 25891250 |
| 2016-02-20 11:19:00 | results suggest that WDR74 is a novel regulatory protein of the MTR4-exsosome complex whose interaction is regulated by NVL2 and is involved in ribosome biogenesis | 26456651 |
| 2015-11-14 10:15:00 | suggest that NVL2 is involved in pre-rRNA processing by associating with the nuclear exosome complex and that MPP6 is required for maintaining the integrity of this rRNA processing complex | 26166824 |
| Type | IDs |
|---|---|
| Synonymous | NVL2 |
| Gene |
UniProtKB-ID:
NVL_HUMAN,
B4DF43_HUMAN
UniprotKB:
O15381,
B4DF43
UniParc:
UPI00017A763A,
UPI00017A7856,
UPI0000073F3E,
UPI00001408D9,
UPI00017A7013,
UPI000007294C
EMBL:
U78772,
AK293923,
AK298244,
U68140,
BC012105,
AC092809,
AK297396
Ensembl:
ENSG00000143748
KO:
hsa:4931
|
| Nucleutide sequences |
EMBL-CDS:
AAB70460.1,
AAH12105.1,
BAG60510.1,
AAB70457.1,
BAG59836.1,
BAG57304.1
Ensembl_TRS:
ENST00000469968,
ENST00000469075,
ENST00000340871,
ENST00000281701,
ENST00000391875,
ENST00000482491
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000281701,
ENSP00000419420,
ENSP00000417213,
ENSP00000417826,
ENSP00000375747,
ENSP00000341362
RefSeq:
XP_016856869.1,
XP_011542501.1,
XP_016856872.1,
NP_001230076.1,
XP_016856871.1,
XP_016856874.1,
XP_016856873.1,
XP_016856868.1,
XP_011542498.1,
NP_001230075.1,
NP_996671.1,
XP_011542502.1,
XP_016856870.1,
NP_002524.2,
XP_024303135.1,
XP_016856867.1,
XP_016856875.1,
XP_011542500.1
|
| Others |
UniRef100:
UniRef100_B4DF43,
UniRef100_O15381
UniRef90:
UniRef90_O15381,
UniRef90_B4DF43
UniRef50:
UniRef50_A0A2J8U290,
UniRef50_O15381
UniGene:
Hs.497867
CCDS:
CCDS58063.1,
CCDS1542.1,
CCDS58062.1,
CCDS1541.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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