| Type | Description |
|---|---|
| Definition | Protein phosphatase 1 at 87B |
| Date | Results | Publications |
|---|---|---|
| 2020-02-22 11:21:00 | Depletion of SUR-8 decreased the interaction of PER and PP1-87B, which supports the role of SUR-8 as a scaffold protein. Interestingly, the interaction between SUR-8 and PER is temporally regulated: SUR-8 has more binding to PER at night than morning. Thus, our results indicate that SUR-8 interacts with PP1-87B to control PER stability to regulate circadian rhythms. | 31710605 |
| 2019-12-07 10:24:00 | Two mechanisms have been proposed to maintain co-orientation in Drosophila oocytes: one involves SPC105R to protect cohesins at sister centromeres, and another involves PP1-87B to regulate spindle forces at end-on attachments. | 31150390 |
| 2018-02-17 11:05:00 | Here the authors show in vitro and in Drosophila that 1 (PP1) inactivates Mps1 by dephosphorylating its T-loop. PP1-mediated dephosphorylation of Mps1 occurs at kinetochores and in the cytosol, and inactivation of both pools of Mps1 during metaphase is essential to ensure prompt and efficient Spindle Assembly Checkpoint silencing. | 28463114 |
| 2016-03-26 10:38:00 | Ectopic expression of dRif1 causes enlarged larval imaginal discs and early pupal lethality which is completely reversed by co-expression of PP1 87B, the major protein phosphatase in Drosophila, indicating genetic and functional interaction | 26022086 |
| 2015-02-21 12:03:00 | these findings shed light on the in vivo role of the PNUTS-PP1 holoenzyme and its contribution to the control of gene expression during early Drosophila development. | 24204300 |
| Type | IDs |
|---|---|
| Synonymous | 87B, CG5650, DmPp1-87B, Dmel\CG5650, PP-1alpha, PP1, PP1 87B, PP1 beta87b, PP1-87B, PP187B, PP1A87B, PP1B, PP1alpha-87B, PP1alpha87B, PP1alpha[[2]], PP1c, PP1c 87B, PPI 87B, Pp-1alpha, Pp1, Pp1-87Bb, Pp1alpha-87B, Ppl-87B, Su(Var)3-6, Su(var)(3)6, Su(var)3-6, Su-var(3)6, Suvar(3)6, ck19, dPP1beta, l(3)87Bg, l(3)ck19, l(3)j6E7, pp1-87B, su-var(3)6 |
| Gene |
UniProtKB-ID:
PP12_DROME
UniprotKB:
P12982
UniParc:
UPI000012488F
EMBL:
S47852,
AE014297,
AY061063,
X15583
EnsemblGenome:
FBgn0004103
KO:
dme:Dmel_CG5650
|
| Nucleutide sequences |
EMBL-CDS:
AAF54810.1,
AAB23957.1,
CAA33609.1,
AAL28611.1
Gene_ORFName:
CG5650
EnsemblGenome_TRS:
FBtr0082595
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0082067
RefSeq:
NP_524937.1
|
| Others |
UniRef100:
UniRef100_P12982
UniRef90:
UniRef90_P12982
UniRef50:
UniRef50_P12982
UniGene:
Dm.1623
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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