| Type | Description |
|---|---|
| Definition | nth like DNA glycosylase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:17:00 | Monoallelic NTHL1 Loss-of-Function Variants and Risk of Polyposis and Colorectal Cancer. | 32860789 |
| 2021-03-28 19:07:00 | NTHL1 in genomic integrity, aging and cancer. | 33087284 |
| 2021-03-27 14:39:00 | An Excimer Clamp for Measuring Damaged-Base Excision by the DNA Repair Enzyme NTH1. | 32109332 |
| 2020-10-31 13:18:00 | NTHL1 biallelic mutations seldom cause colorectal cancer, serrated polyposis or a multi-tumor phenotype, in absence of colorectal adenomas. | 31227763 |
| 2019-12-21 11:39:00 | The results suggest that the NTHL1 variants Q90X, Y130X, R153X, and Q287X, but not R19Q, V179I, V217F, or G286S, were defective in 5OHU repair and the alleles encoding them were considered to be pathogenic for NTHL1-associated polyposis. | 30552997 |
| Type | IDs |
|---|---|
| Synonymous | FAP3, NTH1, OCTS3, hNTH1 |
| Gene |
UniProtKB-ID:
NTH_HUMAN,
E5KTI5_HUMAN
UniprotKB:
P78549,
E5KTI5
UniParc:
UPI00001498A7,
UPI0000130586,
UPI00001498BC
EMBL:
HQ206277,
HQ206283,
HQ206272,
HQ206292,
HQ206286,
HQ206297,
HQ206288,
HQ206273,
HQ206279,
AB014460,
HQ206291,
HQ206303,
BC003014,
HQ206280,
Y09687,
HQ206266,
BC000391,
HQ206295,
U81285,
HQ206304,
HQ206293,
HQ206270,
HQ206282,
HQ206300,
HQ206299,
HQ206274,
HQ206301,
U79718,
HQ206275,
AC005600,
HQ206302,
HQ206290,
HQ206271,
HQ206285,
CH471112,
HQ206298,
HQ206289,
AF498098,
HQ206305,
HQ206278,
HQ206281,
HQ206296,
AB001575,
HQ206267,
HQ206276,
HQ206268,
HQ206269,
HQ206287,
HQ206294,
HQ206284
Ensembl:
ENSG00000065057
KO:
hsa:4913
|
| Nucleutide sequences |
EMBL-CDS:
AAB41534.1,
AAH03014.1,
BAA32695.1,
AAM11786.1,
CAA70865.1,
AAC34209.1,
AAH00391.2,
AAC51136.1,
BAA19413.1,
ADP92236.1,
ADP92250.1,
ADP92226.1,
ADP92222.1,
ADP92238.1,
ADP92235.1,
ADP92252.1,
ADP92221.1,
ADP92253.1,
ADP92229.1,
ADP92243.1,
ADP92223.1,
ADP92225.1,
ADP92219.1,
ADP92218.1,
ADP92247.1,
ADP92246.1,
ADP92227.1,
ADP92216.1,
ADP92234.1,
ADP92232.1,
ADP92214.1,
ADP92233.1,
ADP92224.1,
ADP92230.1,
ADP92237.1,
ADP92217.1,
ADP92241.1,
ADP92244.1,
ADP92249.1,
ADP92240.1,
ADP92215.1,
ADP92242.1,
ADP92228.1,
ADP92248.1,
ADP92239.1,
ADP92231.1,
EAW85562.1,
ADP92245.1,
ADP92220.1,
ADP92251.1
Gene_ORFName:
hCG_1989994
Ensembl_TRS:
ENST00000219066,
ENST00000651570
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000219066,
ENSP00000498421
RefSeq:
NP_001305123.1,
NP_002519.2,
NP_001305122.2
|
| Others |
UniRef100:
UniRef100_P78549
UniRef90:
UniRef90_P78549
UniRef50:
UniRef50_P78549
UniGene:
Hs.66196
CCDS:
CCDS10457.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.proteinEnsembl}} |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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