| Type | Description |
|---|---|
| Definition | G protein-coupled receptor kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2016-06-28 10:33:00 | pleckstrin homology domain of Gprk2 essential for enriching PI(4)P and facilitating Smo activation | 26863604 |
| 2015-02-14 13:33:00 | Gprk2 phosphorylation in the membrane proximal C-terminus is an evolutionarily ancient mechanism of Smo regulation, and point to a higher degree of similarity in the regulation and signaling mechanisms of bilaterian Smo proteins | 25009998 |
| 2013-12-14 11:15:00 | based on findings, propose that Gprk2 attenuates and tunes Fog-Cta signaling to prevent apical constriction in lateral mesodermal cells and to support appropriate apical constriction in ventral mesodermal cells | 24026125 |
| 2012-02-04 11:33:00 | Drosophila G-protein-coupled receptor kinase 2 regulates cAMP-dependent Hedgehog signaling. | 22096079 |
| 2010-11-06 11:06:00 | G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in Drosophila | 20844016 |
| Type | IDs |
|---|---|
| Synonymous | 154978_at, CG17998, Dmel\CG17998, Gprk 2, Gprk-2, gprk2, nosh |
| Gene |
UniProtKB-ID:
GPRK2_DROME,
A0A0B4KI69_DROME
UniprotKB:
P32866,
A0A0B4KI69
UniParc:
UPI0000124703
EMBL:
M80494,
AF004674,
AE014297,
AY051949,
BT031258
EnsemblGenome:
FBgn0261988
KO:
dme:Dmel_CG17998
|
| Nucleutide sequences |
EMBL-CDS:
AAA28589.1,
AAB61467.1,
AAK93373.1,
ABY20499.1,
AAF57152.1,
AGB96522.1
Gene_ORFName:
CG17998,
CG17998,
Dmel_CG17998
EnsemblGenome_TRS:
FBtr0085788,
FBtr0334555,
FBtr0085788,
FBtr0334555
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0306622,
FBpp0085149,
FBpp0085149,
FBpp0306622
RefSeq:
NP_476867.1,
NP_001263143.1
|
| Others |
UniRef100:
UniRef100_P32866
UniRef90:
UniRef90_P32866
UniRef50:
UniRef50_P32866
UniGene:
Dm.4430
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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