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4902 NRTN

4902

NRTN

neurturin

protein-coding

Homo sapiens

基因描述

Type Description
Definition neurturin

研究结论

Date Results Publications
2021-01-09 13:26:00 Refolding and purification of cGMP-grade recombinant human neurturin from Escherichia coli inclusion bodies. 31866372
2020-05-02 10:52:00 We have reconstituted the complete extracellular region of the RET signaling complex together with Neurturin (NRTN) and GFRalpha2 and determined its structure at 5.7-A resolution by cryo-EM. The proteins form an assembly through RET-GFRalpha2 and RET-NRTN interfaces. 31392261
2018-12-22 10:44:00 biophysical results show that the relative concentration of GFRa2 on cell surfaces can affect the functional affinity of NRTN through avidity effects. 29414779
2014-10-25 11:29:00 In the cochlea, NTN immunostaining was found in the supporting cells of organ of Corti, including Deiters' cells, Hensen cells as well as Claudius' cells. In the spiral ganglia, NTN was seen in both the cell bodies and the nerve fibers of neurons. 24139947
2014-04-05 13:44:00 Neurturin contributes toward an aggressive cancer cell phenotype, neuropathic pain and neuronal plasticity in pancreatic cancer. 24067900

名称对应

Type IDs
Synonymous NTN
Gene
UniProtKB-ID: NRTN_HUMAN
UniprotKB: Q99748
UniParc: UPI0000050F8C
EMBL: AL161995, BC137399, CH471139, U78110, BC137400
Ensembl: ENSG00000171119
KO: hsa:4902
Nucleutide sequences
EMBL-CDS: EAW69140.1, AAI37400.1, AAI37401.1, AAC50898.1, CAB82327.1
Ensembl_TRS: ENST00000303212
Protein sequencees
Ensembl_PRO: ENSP00000302648
RefSeq: NP_004549.1
Others
UniRef100: UniRef100_Q99748
UniRef90: UniRef90_Q99748
UniRef50: UniRef50_Q99748
UniGene: Hs.234775
CCDS: CCDS12151.1

全选

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研究热度

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