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48973 Src64B

48973

Src64B

Src oncogene at 64B

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Src oncogene at 64B

研究结论

Date Results Publications
2018-10-20 11:47:00 Src overexpression alone activated the Jun N-terminal Kinase (JNK) signalling pathway to promote actin cytoskeletal and cell polarity defects and drive apoptosis in in a whole epithelial tissue context in the Drosophila eye, whereas, in cooperation with RasACT, JNK led to a loss of differentiation and an invasive phenotype. 29861494
2016-05-28 11:12:00 Src64 controls actin dynamics to mediate proper ring canal formation during incomplete cytokinesis during germline cyst development in vivo 26628094
2015-07-25 12:04:00 that Brat represses the translation of src64B, an upstream regulator of a conserved Rho-dependent pathway previously shown to promote axon retraction 25297111
2015-07-25 10:08:00 Results show that Src42a and Src64b are required for the normal division capacity of Drosophila intestinal progenitor cells, and that these genes as well as Ack cause progenitor overproliferation in the intestine via core cell cycle activation. 24975577
2014-09-06 12:06:00 a novel essential role for Src in intestinal stem/progenitor cell proliferation and tumourigenesis initiation in vivo. 24788409

名称对应

Type IDs
Synonymous C-src1, CG7524, D-Src64B, D-src, DSRC64, DSrc, DSrc64, DSrc64B, Dm SRC1, DmHD-358, Dmel\CG7524, Dsrc, Dsrc64, Dsrc64B, HD-358, MRE5, SRC 64B, SRC64B, Src, Src1, Src64, Src64b, c-src, dSrc, dsrc, src, src1, src64, src64B, src64b
Gene
UniProtKB-ID: SRC64_DROME, M9MSK3_DROME, X2JCI2_DROME
UniprotKB: P00528, M9MSK3, X2JCI2
UniParc: UPI0003954CA4, UPI0000124921
EMBL: AY051781, AE014296, M11917, AJ002919, K01043
EnsemblGenome: FBgn0262733
KO: dme:Dmel_CG7524
Nucleutide sequences
EMBL-CDS: AAK93205.1, AAA28489.1, AAX52734.1, AAF47922.1, AAX52737.1, CAA05754.1, AAX52735.1, AAX52736.1, AAA28913.1, AFH04299.1, AFH04300.1, ADV37488.1, AHN57962.1
Gene_ORFName: CG7524, Dmel_CG7524, CG7524, CG7524, Dmel_CG7524
EnsemblGenome_TRS: FBtr0100507, FBtr0304989, FBtr0073321, FBtr0100504, FBtr0100505, FBtr0100508, FBtr0304990, FBtr0302594, FBtr0304990, FBtr0073321, FBtr0100505, FBtr0100508, FBtr0304989, FBtr0100504, FBtr0100507, FBtr0302594, FBtr0343995
Protein sequencees
EnsemblGenome_PRO: FBpp0293526, FBpp0099946, FBpp0099944, FBpp0291750, FBpp0293527, FBpp0073177, FBpp0099947, FBpp0099948, FBpp0099946, FBpp0073177, FBpp0099948, FBpp0099944, FBpp0293527, FBpp0099947, FBpp0291750, FBpp0293526, FBpp0310444
RefSeq: NP_001246628.1, NP_001014564.1, NP_001014563.1, NP_524934.2, NP_001189051.1, NP_001286937.1, NP_001014562.1, NP_001014561.1, NP_001246629.1
Others
UniRef100: UniRef100_P00528, UniRef100_X2JCI2
UniRef90: UniRef90_P00528, UniRef90_X2JCI2
UniRef50: UniRef50_X2JCI2, UniRef50_P00528
UniGene: Dm.1531

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研究热度

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