| Type | Description |
|---|---|
| Definition | phosphoinositide-3-kinase regulatory subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:59:00 | We assessed the genomic landscape of canine hemangiosarcoma via whole-exome sequencing (47 golden retriever hemangiosarcomas) and RNA sequencing (74 hemangiosarcomas from multiple breeds). Somatic coding mutations occurred most frequently in the tumor suppressor TP53 (59.6% of cases) as well as two genes in the PI3K pathway: the oncogene PIK3CA (29.8%) and its regulatory subunit PIK3R1 (8.5%). | 31570656 |
| 2010-01-21 00:00:00 | is involved upstream of PI3-Kinase in the suppression of Na,K-Beta mediated cell motility in carcinoma cells.(Na,K-Beta1) | 17535735 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
F1Q2Q9_CANLF,
A0A5F4BQR4_CANLF,
A0A5F4CI88_CANLF
UniprotKB:
F1Q2Q9,
A0A5F4BQR4,
A0A5F4CI88
UniParc:
UPI00004BD246,
UPI00004BD243,
UPI00004BD245
EMBL:
AAEX03001491
Ensembl:
ENSCAFG00000007626
KO:
cfa:487235
|
| Nucleutide sequences |
Ensembl_TRS:
ENSCAFT00000012216,
ENSCAFT00000076972,
ENSCAFT00000061673
|
| Protein sequencees |
Ensembl_PRO:
ENSCAFP00000011322,
ENSCAFP00000043843,
ENSCAFP00000054020
RefSeq:
XP_013964299.1,
XP_022265842.1,
XP_013964297.1,
XP_003433863.1,
XP_544363.2
|
| Others |
UniRef100:
UniRef100_F1Q2Q9,
UniRef100_A0A337S1J0,
UniRef100_A0A5F4BQR4
UniRef90:
UniRef90_P27986,
UniRef90_A0A2I2UZ02,
UniRef90_P27986-2
UniRef50:
UniRef50_P27986,
UniRef50_P27986-2
UniGene:
Cfa.4502
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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