| Type | Description |
|---|---|
| Definition | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:25:00 | Atomistic Structure and Dynamics of the Ca(2+)-ATPase Bound to Phosphorylated Phospholamban. | 33019581 |
| 2018-01-27 10:06:00 | Study demonstrated that (a) the distribution and the expression levels of total SERCA1 and SERCA2, the activity of SR Ca2+ ATPase, and the oligomerization of SERCA1 are similar in patients with myotonic dystrophy 1, myotonic dystrophy 2, hypothyroid myopathy and control subjects; and (b) SERCA1b is expressed in patients with myotonic dystrophy, mainly in myotonic dystrophy 2 muscles. | 27133661 |
| 2017-07-08 10:08:00 | These results suggest that sAnk1 interacts with SLN both directly and in complex with SERCA1 and reduces SLN's inhibitory effect on SERCA1 activity. | 28487373 |
| 2016-10-22 12:05:00 | CAPN3 deficiency leads to degradation of SERCA proteins and Ca2+ dysregulation in the skeletal muscle. | 27055500 |
| 2016-09-03 11:38:00 | The sphingolipid sphingosine increases the [Ca(2+)]i by inhibiting the sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA), in a similar manner to thapsigargin (Tg), a specific inhibitor of this Ca(2+) pump. | 27033604 |
| Type | IDs |
|---|---|
| Synonymous | ATP2A, SERCA1 |
| Gene |
UniProtKB-ID:
AT2A1_HUMAN,
Q7Z675_HUMAN
UniprotKB:
O14983,
Q7Z675
UniParc:
UPI000002A426,
UPI000003B461,
UPI00004A2975,
UPI00001A9CE1
EMBL:
AC133550,
BX537784,
U96774,
U96777,
AC109460,
U96779,
U96780,
AK291314,
U96775,
AK128456,
U96773,
U96778,
U96776,
U96781
Ensembl:
ENSG00000196296
KO:
hsa:487
|
| Nucleutide sequences |
EMBL-CDS:
AAB53112.1,
AAB53113.1,
BAG54679.1,
BAF84003.1,
CAD97841.1
Ensembl_TRS:
ENST00000357084,
ENST00000395503,
ENST00000536376
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000443101,
ENSP00000349595,
ENSP00000378879
RefSeq:
NP_001273004.1,
NP_775293.1,
NP_004311.1
|
| Others |
UniRef100:
UniRef100_Q7Z675,
UniRef100_O14983
UniRef90:
UniRef90_P04191
UniRef50:
UniRef50_P04191
UniGene:
Hs.657344
CCDS:
CCDS42139.1,
CCDS10643.1,
CCDS66997.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员