| Type | Description |
|---|---|
| Definition | NOVA alternative splicing regulator 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:25:00 | MiR-7-5p suppresses tumor metastasis of non-small cell lung cancer by targeting NOVA2. | 31832068 |
| 2020-05-16 11:46:00 | The NOVA2 variant protein shows decreased ability to bind target RNA sequences. | 32197073 |
| 2020-03-21 12:18:00 | Here, the authors report that endothelial cells (ECs) express a novel isoform of the cell-surface adhesion molecule L1CAM, termed L1-DeltaTM. The splicing factor NOVA2, which binds directly to L1CAM pre-mRNA, is necessary and sufficient for the skipping of L1CAM transmembrane domain in ECs, leading to the release of soluble L1-DeltaTM. | 30829570 |
| 2020-01-11 10:57:00 | Authors identify a mechanism whereby Nova2-regulated splicing constrains Erk signaling, thus limiting lymphatic progenitor cell specification. | 31014480 |
| 2010-01-21 00:00:00 | SCN1A polymorphism has a dramatic effect on the proportions of neonate and adult alternative transcripts of SCN1A in adult brain tissue and, the effect of the polymorphism also appears to be modified by Nova2 expression levels. | 17436242 |
| Type | IDs |
|---|---|
| Synonymous | ANOVA, NOVA3 |
| Gene |
UniProtKB-ID:
NOVA2_HUMAN
UniprotKB:
Q9UNW9
UniParc:
UPI000006EBE8
EMBL:
AC006540,
U70477,
AF083898
Ensembl:
ENSG00000104967
KO:
hsa:4858
|
| Nucleutide sequences |
EMBL-CDS:
AAC72355.1,
AAD13116.1,
AAB88661.1
Ensembl_TRS:
ENST00000263257
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000263257
RefSeq:
XP_006723293.1,
XP_016882329.1,
XP_016882328.1,
XP_016882327.1,
NP_002507.1
|
| Others |
UniRef100:
UniRef100_Q9UNW9
UniRef90:
UniRef90_Q9UNW9
UniRef50:
UniRef50_Q9UNW9
UniGene:
Hs.375439
CCDS:
CCDS12679.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员