| Type | Description |
|---|---|
| Definition | N-myristoyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-21 11:26:00 | mTOR, a downstream target of PKB/Akt, regulates NMT1 in ER positive breast cancer cells (MCF7 cells). NMT1 increased with rapamycin treatment over the period of time with a concomitant decrease in mTOR phosphorylation. | 30154572 |
| 2019-12-14 11:25:00 | inhibition of NMT1 caused degraded proteins increase and ER stress, which cross-talked with mitochondria to produce more And both of oxidative stress and ER stress could activate JNK pathway, leading to autophagy which abrogated breast cancer progression especially triple-negative breast cancer (TNBC). | 30446635 |
| 2019-05-04 10:57:00 | Data showed that rheumatoid arthritis (RA) T cells had a defect in type I N-myristoyltransferase (NMT1) function, which prevented AMP-activated protein kinase (AMPK) activation. | 30718913 |
| 2018-01-06 10:58:00 | Genetic and pharmacologic evidence that inhibiting the N-myristoyltransferase NMT1 suppresses cell-cycle progression, proliferation, and malignant growth of prostate cancer cells. | 29038344 |
| 2016-04-23 10:09:00 | These observations point at a previously unrecognized contribution of calnexin to the retention of NMT1 at the ER membrane. | 26603938 |
| Type | IDs |
|---|---|
| Synonymous | NMT |
| Gene |
UniProtKB-ID:
NMT1_HUMAN
UniprotKB:
P30419
UniParc:
UPI0000130275,
UPI000002AF50
EMBL:
Y17209,
M86707,
AF043324,
AF020500,
BC008312,
Y17208,
AK291936,
BC006538,
BC007258,
CH471178,
BC006569
Ensembl:
ENSG00000136448
KO:
hsa:4836
|
| Nucleutide sequences |
EMBL-CDS:
AAH06538.1,
EAW51554.1,
CAA76686.1,
AAH07258.2,
CAA76685.1,
AAH06569.1,
BAF84625.1,
AAH08312.2,
AAB95316.1,
AAC09294.1
Ensembl_TRS:
ENST00000258960,
ENST00000592782
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000258960,
ENSP00000468424
RefSeq:
NP_066565.1
|
| Others |
UniRef100:
UniRef100_P30419
UniRef90:
UniRef90_P30419
UniRef50:
UniRef50_P30419
UniGene:
Hs.532790
CCDS:
CCDS11494.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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