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4835 NQO2

4835

NQO2

N-ribosyldihydronicotinamide:quinone reductase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition N-ribosyldihydronicotinamide:quinone reductase 2

研究结论

Date Results Publications
2020-09-19 16:25:00 Cancer-associated variants of human NQO1: impacts on inhibitor binding and cooperativity. 31431515
2019-06-29 10:39:00 these data suggest that the overexpression of QR2 in brain cells in the presence of catechol quinones might lead to reactive oxygen species-induced cell death via the rapid conversion of superoxide radicals into hydrogen peroxide and then into highly reactive hydroxyl radicals 29526807
2017-12-23 10:49:00 The ontogeny and population variability of human hepatic dihydronicotinamide riboside:quinone oxidoreductase (NQO2). 28346733
2016-03-19 11:40:00 In patients with Alzheimer's disease, QR2 is overexpressed in the insular cotex. 26609153
2014-06-28 13:02:00 NQO2-L47 is less stable towards proteolytic digestion and thermal denaturation than NQO2-F47. 24631540

名称对应

Type IDs
Synonymous DHQV, DIA6, NMOR2, QR2
Gene
UniProtKB-ID: NQO2_HUMAN, Q5TD07_HUMAN, B3KPX6_HUMAN
UniprotKB: P16083, Q5TD07, B3KPX6
UniParc: UPI000020E417, UPI0000371AC0, UPI000020E40D
EMBL: AB050248, AL133351, J02888, AK311746, AK056981, CH471087, AY299456, AY855291, BC006096
Ensembl: ENSG00000124588
KO: hsa:4835
Nucleutide sequences
EMBL-CDS: AAA60239.1, BAG34689.1, BAB16974.1, EAW55107.1, AAH06096.1, AAB60642.3, AAW29945.1, BAG51838.1
Ensembl_TRS: ENST00000338130, ENST00000380430, ENST00000380455, ENST00000380454, ENST00000380441
Protein sequencees
Ensembl_PRO: ENSP00000369795, ENSP00000369822, ENSP00000337773, ENSP00000369821, ENSP00000369806
RefSeq: NP_000895.2, NP_001277151.1, NP_001277150.1, NP_001305869.1
Others
UniRef100: UniRef100_B3KPX6, UniRef100_P16083, UniRef100_Q5TD07
UniRef90: UniRef90_P16083, UniRef90_Q5TD07
UniRef50: UniRef50_P16083, UniRef50_Q5TD07
UniGene: Hs.145597, Hs.533050
CCDS: CCDS4481.1

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