| Type | Description |
|---|---|
| Definition | nitrilase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 10:36:00 | NIT1 suppresses colorectal cancer cell proliferation through a positive feedback loop between NIT1 and activation of the TGFbeta-Smad2/3 signalling pathway. | 29449642 |
| 2017-12-09 11:40:00 | Data show that cisplatin response was enhanced in human lung cancer cells when Nit1 was knocked down and mice Nit1-/-:KrasG12D/+ tumors showed increased sensitivity to cisplatin in vivo. | 26967383 |
| 2015-10-31 11:19:00 | Human NIT1/2 are not involved in the metabolism of vildagliptin. | 25008847 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20877624 |
| 2010-01-21 00:00:00 | Nit1 and Fhit share tumor suppressor signaling pathways, while localization of the NIT1 gene at a stable chromosome site explains the paucity of gene alterations and in frequent loss of expression of the NIT1 gene in human malignancies. | 16864578 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
NIT1_HUMAN,
B7Z410_HUMAN
UniprotKB:
Q86X76,
B7Z410
UniParc:
UPI0000418DB4,
UPI00004701D4,
UPI0001914BF1,
UPI0000418DB3,
UPI0000204BF2,
UPI00000715F9
EMBL:
CH471121,
CR541846,
AF069984,
CR541814,
AK296606,
BC046149,
AF069987,
AL591806
Ensembl:
ENSG00000158793
KO:
hsa:4817
|
| Nucleutide sequences |
EMBL-CDS:
AAC39901.1,
AAC39907.1,
EAW52656.1,
CAG46613.1,
AAH46149.1,
EAW52657.1,
CAG46644.1,
EAW52654.1,
BAH12396.1
Ensembl_TRS:
ENST00000392190,
ENST00000368008,
ENST00000368007,
ENST00000368009
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000356987,
ENSP00000376028,
ENSP00000356988,
ENSP00000356986
RefSeq:
XP_005245271.1,
XP_005245273.1,
XP_024303131.1,
NP_001172021.1,
XP_005245272.1,
NP_001172022.1,
NP_001172023.1,
XP_016856860.1,
NP_005591.1
|
| Others |
UniRef100:
UniRef100_B7Z410,
UniRef100_Q86X76
UniRef90:
UniRef90_Q86X76-3,
UniRef90_Q86X76
UniRef50:
UniRef50_Q86X76
UniGene:
Hs.146406
CCDS:
CCDS53403.1,
CCDS1218.1,
CCDS53401.1,
CCDS53402.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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