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4801 NFYB

4801

NFYB

nuclear transcription factor Y subunit beta

protein-coding

Homo sapiens

基因描述

Type Description
Definition nuclear transcription factor Y subunit beta

研究结论

Date Results Publications
2018-10-27 12:12:00 The nuclear transcription factor Y subunit beta (NFYB)-E2F transcription factor 1 (E2F1) pathway displays a crucial role in the chemoresistance ofoxaliplatin-resistant colorectal cancer (OR-CRC) by inducing the expression and activation of checkpoint kinase 1 (CHK1), suggesting a possible therapeutic target for oxaliplatin resistance in CRC. 29203250
2016-12-17 10:44:00 Data indicate that specific cancer-driving nodes are generally under NF-YA/B control. 26646448
2016-10-22 11:23:00 Presence of NF-Y transcription factor plays a pivotal role in transcriptional regulation of ID genes in development. 26509926
2016-05-07 10:44:00 NF-YB transcription factor was identified as a novel direct E2F1 target. 26039627
2014-02-22 12:26:00 The NF-Y complex is asymmetric, with NF-YB binding approximately 15 bp downstream from the CCAAT motif. 23595228

名称对应

Type IDs
Synonymous CBF-A, CBF-B, HAP3, NF-YB
Gene
UniProtKB-ID: NFYB_HUMAN, A0A024RBG7_HUMAN, F8VSL3_HUMAN
UniprotKB: P25208, A0A024RBG7, F8VSL3
UniParc: UPI0000127178, UPI0000EE27B2
EMBL: AC089983, CH471054, L06145, BC007035, AK291934, BC005317, BC005316, X59710
Ensembl: ENSG00000120837
KO: hsa:4801
Nucleutide sequences
EMBL-CDS: AAH05316.1, AAH05317.1, AAA59930.1, BAF84623.1, AAH07035.1, CAA42230.1, EAW97740.1, EAW97741.1, EAW97742.1, EAW97738.1
Gene_ORFName: hCG_1811685, hCG_1811685
Ensembl_TRS: ENST00000551727, ENST00000240055, ENST00000551446
Protein sequencees
Ensembl_PRO: ENSP00000240055, ENSP00000447486, ENSP00000448250
RefSeq: XP_005268965.1, XP_005268966.1, XP_005268967.1, XP_024304752.1, XP_024304753.1, NP_006157.1
Others
UniRef100: UniRef100_F8VSL3, UniRef100_P25208
UniRef90: UniRef90_P25208
UniRef50: UniRef50_P25208
UniGene: Hs.84928
CCDS: CCDS9098.1

全选

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