| Type | Description |
|---|---|
| Definition | nuclear transcription factor Y subunit alpha |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 12:57:00 | NF-YA Overexpression in Lung Cancer: LUAD. | 32075093 |
| 2020-10-31 13:14:00 | Overexpression and alternative splicing of NF-YA in breast cancer. | 31506469 |
| 2020-05-09 13:18:00 | By interrogating RNA-seq TCGA and GEO datasets study found that unlike NF-YB/NF-YC, NF-YAs is overexpressed in lung squamous cell carcinomas. The ratio of the two isoforms changes from normal to cancer cells, with NF-YAs becoming predominant in the latter. NF-YA increased expression correlates with common proliferation markers and worse clinical outcome. | 31744190 |
| 2020-04-25 12:43:00 | NF-YA overexpressing prevents activation of the pro-apoptotic transcription factor CHOP/DDIT3 and elevated basal levels of SERCA1/2, coding for the molecular target of Thapsigargin, correlate with resistance of NF-YA OE cells to the drug. | 31706909 |
| 2020-02-22 10:04:00 | This study identified NF-YA box CCAAT as a key cis-element in the SOX2 promoter, suggesting that NF-YA is a potent cellular regulator in the maintenance of SOX2-positive cervical cancer stem cell by specific transcriptional activation of SOX2. | 31365524 |
| Type | IDs |
|---|---|
| Synonymous | CBF-A, CBF-B, HAP2, NF-YA |
| Gene |
UniProtKB-ID:
NFYA_HUMAN,
A0A024RD22_HUMAN
UniprotKB:
P23511,
A0A024RD22
UniParc:
UPI000012717C,
UPI000002A57F
EMBL:
AL031778,
M59079,
X59711,
BC039244,
CH471081
Ensembl:
ENSG00000001167
KO:
hsa:4800
|
| Nucleutide sequences |
EMBL-CDS:
CAA42231.1,
AAA35950.1,
AAH39244.1,
EAX04016.1,
EAX04013.1,
EAX04019.1
Gene_ORFName:
hCG_33333
Ensembl_TRS:
ENST00000341376,
ENST00000353205
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000229418,
ENSP00000345702
RefSeq:
NP_068351.1,
NP_002496.1
|
| Others |
UniRef100:
UniRef100_A0A024RD22,
UniRef100_P23511
UniRef90:
UniRef90_P18576,
UniRef90_P23511
UniRef50:
UniRef50_P23511
UniGene:
Hs.10441
CCDS:
CCDS4850.1,
CCDS4849.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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