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48 ACO1

48

ACO1

aconitase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition aconitase 1

研究结论

Date Results Publications
2020-10-24 14:08:00 Cellular iron sensing and regulation: Nuclear IRP1 extends a classic paradigm. 32199885
2019-05-18 12:06:00 HIF-1alpha overexpression enhanced the mRNA levels of TfR1 and DMT1(+IRE), which reversed the inhibition of IRP1 on both. 30415773
2018-12-01 12:13:00 These results support the concept that IRP1 is an oxidative stress biosensor that mediates iron accumulation and cell death when deregulated by mitochondrial dysfunction. 28502703
2018-09-22 11:44:00 Results indicate that there is a dysregulation of DMT1 + IRE in IA testes, which might due to the up-regulation of IRP1 and HIF-1A. 28762519
2018-08-11 11:14:00 Evaluation of the iron regulatory protein-1 interactome has been presented. 29330752

名称对应

Type IDs
Synonymous ACONS, HEL60, IREB1, IREBP, IREBP1, IRP1
Gene
UniProtKB-ID: ACOC_HUMAN, Q9HBB2_HUMAN, V9HWB7_HUMAN
UniprotKB: P21399, Q9HBB2, V9HWB7
UniParc: UPI000012D87E, UPI0000073F22
EMBL: GQ891435, Z11559, AL161783, M58510, CH471071, BC018103, AF261088, DQ496106, EU794627
Ensembl: ENSG00000122729
KO: hsa:48
Nucleutide sequences
EMBL-CDS: EAW58550.1, EAW58549.1, EAW58552.1, AAH18103.1, CAA77651.1, ABF47095.1, AAA69900.1, AAF99681.1, ACJ13681.1, ADO22297.1
Ensembl_TRS: ENST00000309951, ENST00000379923, ENST00000541043
Protein sequencees
Ensembl_PRO: ENSP00000309477, ENSP00000438733, ENSP00000369255
RefSeq: XP_011516190.1, NP_002188.1, NP_001265281.1, NP_001349769.1
Others
UniRef100: UniRef100_P21399
UniRef90: UniRef90_P21399
UniRef50: UniRef50_P21399
UniGene: Hs.567229
CCDS: CCDS6525.1

全选

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研究热度

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