| Type | Description |
|---|---|
| Definition | nuclear transcription factor, X-box binding 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 11:42:00 | we found that NFX1-123 was a bona fide substrate of the deubiquitinase USP9X and that it could be degraded by the ubiquitin-proteasome system. The present study provided new insight into understanding the biological function of USP9X by targeting its substrate NFX1-123. | 31059266 |
| 2020-05-16 11:54:00 | initial mRNP binding to the NPC did not require NXF1 in the NPC, whereas release into the cytoplasm did. NXF1 localization in the NPC did not require RNA or RNA binding. Superresolution microscopy showed that NXF1 consistently occupied positions on the cytoplasmic side of the NPC. | 31375530 |
| 2020-01-25 11:35:00 | Results indicate that NFX1-123 is markedly increased in cervical cancer, its greater expression in 16E6 expressing cells is associated with improved growth and telomerase activity, and that this association is maintained in HPV 16 positive cervical cancer cell lines. | 30776478 |
| 2019-10-26 10:49:00 | NFX1-123 in mediating epithelial differentiation through the JNK signaling pathway. | 30903928 |
| 2017-12-02 12:15:00 | This study identifies NFX1-123 as a critical host protein partner through which 16E6 is able to subvert the immune response and in turn permit a long-lived high-risk Human papillomavirus infection. | 29117186 |
| Type | IDs |
|---|---|
| Synonymous | NFX2, TEG-42, Tex42 |
| Gene |
UniProtKB-ID:
NFX1_HUMAN
UniprotKB:
Q12986
UniParc:
UPI0000072846,
UPI000016064D,
UPI0000072140
EMBL:
CH471071,
AL356218,
AL356472,
U15306,
AF332009,
BC012151,
AK291643
Ensembl:
ENSG00000086102
KO:
hsa:4799
|
| Nucleutide sequences |
EMBL-CDS:
BAF84332.1,
EAW58510.1,
AAH12151.1,
EAW58511.1,
AAA69517.1,
AAK16545.1
Ensembl_TRS:
ENST00000318524,
ENST00000379540
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000368856,
ENSP00000317695
RefSeq:
NP_001305687.1,
NP_002495.2,
NP_667345.1
|
| Others |
UniRef100:
UniRef100_Q12986
UniRef90:
UniRef90_Q12986
UniRef50:
UniRef50_Q12986
UniGene:
Hs.413074
CCDS:
CCDS6538.1,
CCDS6540.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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