| Type | Description |
|---|---|
| Definition | NFKB inhibitor epsilon |
| Date | Results | Publications |
|---|---|---|
| 2017-08-05 10:30:00 | identify NFKBIE aberrations as a common genetic event across B-cell malignancies and highlight NFKBIE deletions as a novel poor-prognostic marker in PMBL. | 27670424 |
| 2017-05-06 11:03:00 | We suggest that the impairment of NFKBIE gene function can reduce the uptake of methotrexate into cells, suggesting that the gene is an important factor for rheumatoid arthritis outcome | 26587663 |
| 2016-11-05 12:14:00 | A NFKBIE polymorphism was associated with increased risk of pneumococcal meningitis. | 26870821 |
| 2016-09-03 11:57:00 | results show that Gal-1 acts by inhibiting the stimulation of the LPS-induced IkappaBzeta expression, an NF-kappaB regulator involved in IL-6 gene transcription. | 26226212 |
| 2016-01-02 10:56:00 | Newly identified alterations included recurrent promoter mutations of NFKBIE, encoding NF-kappaB inhibitor varepsilon (IkappaBvarepsilon), in 14.5% of samples of desmoplastic melanoma | 26343386 |
| Type | IDs |
|---|---|
| Synonymous | IKBE |
| Gene |
UniProtKB-ID:
IKBE_HUMAN,
Q96F31_HUMAN,
A0A024RD24_HUMAN,
Q7LC14_HUMAN
UniprotKB:
O00221,
Q96F31,
A0A024RD24,
Q7LC14
UniParc:
UPI000013DA3C,
UPI000000123A,
UPI0000227DDD
EMBL:
BC011676,
BC063609,
CH471081,
AK301360,
U91616,
AF261937,
AL139392
Ensembl:
ENSG00000146232
KO:
hsa:4794
|
| Nucleutide sequences |
EMBL-CDS:
AAC51216.1,
EAX04262.1,
AAH63609.1,
AAH11676.2,
EAX04263.1,
AAM27002.1,
BAH13464.1
Gene_ORFName:
hCG_18999
Ensembl_TRS:
ENST00000275015,
ENST00000619360
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000275015,
ENSP00000480216
RefSeq:
NP_004547.3
|
| Others |
UniRef100:
UniRef100_O00221
UniRef90:
UniRef90_O00221
UniRef50:
UniRef50_O00221
UniGene:
Hs.458276
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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