| Type | Description |
|---|---|
| Definition | NFKB inhibitor beta |
| Date | Results | Publications |
|---|---|---|
| 2018-06-23 11:11:00 | The subcellular distributions of IkappaB and NFkappaB are indicative of carcinogenesis. Inhibition of XPO1 results in intranuclear retention of IkappaB, which inhibits NFkappaB and thereby provides a novel mechanism for drug therapy in sarcoma. This effect can be further enhanced in relatively selinexor-resistant sarcoma cell lines by pretreatment with the proteasome inhibitor carfilzomib. | 28314790 |
| 2018-02-10 11:55:00 | data suggest that miRNA-4776 modulates Influenza A virus production in infected cells through NFKBIB expression, possibly through the modulation of NF-kappaB. | 28448456 |
| 2016-02-13 12:08:00 | our data establish the importance of a novel tumor suppressive IKBB gene in abrogating angiogenesis in NPC via the NF-kappaB signalling pathway. | 26227166 |
| 2015-05-30 10:23:00 | NFKBIBrs3136641TT single nucleotide polymorphism was associated with a significantly decreased risk of developing wheezing. | 25326706 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20140262 |
| Type | IDs |
|---|---|
| Synonymous | IKBB, TRIP9 |
| Gene |
UniProtKB-ID:
IKBB_HUMAN,
G5E9C2_HUMAN
UniprotKB:
Q15653,
G5E9C2
UniParc:
UPI00021A89BC,
UPI000013F5A0,
UPI000006FFE4
EMBL:
AK290569,
L40407,
BT006743,
AC011455,
AY736284,
BC007197,
BC015528,
CH471126
Ensembl:
ENSG00000282905,
ENSG00000104825
KO:
hsa:4793
|
| Nucleutide sequences |
EMBL-CDS:
EAW56843.1,
AAH07197.1,
BAF83258.1,
AAU10088.1,
AAP35389.1,
AAC41742.1,
AAH15528.1
Ensembl_TRS:
ENST00000572515,
ENST00000635517,
ENST00000313582,
ENST00000634647,
ENST00000392079
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000489145,
ENSP00000489138,
ENSP00000312988,
ENSP00000459728,
ENSP00000375929
RefSeq:
NP_002494.2,
XP_006723289.2,
XP_006723290.3,
NP_001230045.1,
NP_001356628.1,
NP_001356629.1
|
| Others |
UniRef100:
UniRef100_Q15653
UniRef90:
UniRef90_Q15653
UniRef50:
UniRef50_Q15653
UniGene:
Hs.9731
CCDS:
CCDS12524.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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