| Type | Description |
|---|---|
| Definition | IQ motif containing GTPase activating protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-09-09 10:31:00 | Deletion of IQGAP1 reduces MAPK pathway activation in cell lines, similar to effects seen in human BrafV600E cell lines. | 28445541 |
| 2015-12-26 10:56:00 | IQGAP1 modulates TJ formation by a twofold mechanism: (1) controlling the expression and recruitment of claudin 2 and recruitment of claudin 4 to the TJ, and (2) transient inhibition of the CDC42-JNK pathway. | 25588839 |
| 2014-03-15 11:33:00 | Through its IQ motifs, IQGAP1 binds to EGFR, which is responsible for maintaining IQGAP1 in the basolateral membrane domain. | 24421325 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
F1PJ65_CANLF
UniprotKB:
F1PJ65
UniParc:
UPI00005A04E6
EMBL:
AAEX03002336,
AAEX03002337,
AAEX03002338
Ensembl:
ENSCAFG00000012639
KO:
cfa:479050
|
| Nucleutide sequences |
Ensembl_TRS:
ENSCAFT00000020334
|
| Protein sequencees |
Ensembl_PRO:
ENSCAFP00000018867
RefSeq:
XP_536199.2
|
| Others |
UniRef100:
UniRef100_F1PJ65
UniRef90:
UniRef90_F1PJ65
UniRef50:
UniRef50_P46940
UniGene:
Cfa.774
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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