| Type | Description |
|---|---|
| Definition | ATPase H+/K+ transporting non-gastric alpha2 subunit |
| Date | Results | Publications |
|---|---|---|
| 2020-01-11 10:39:00 | Study in fresh bronchial samples and in cultured epithelial cells found that ATP12A expressed almost exclusively at the apical side of non-ciliated cells of airway epithelium and in submucosal glands, with much higher expression in cystic fibrosis samples. ATP12A upregulation is associated with depletion of K+ in airway surface liquid, an effect that may have an important role in the barrier function of airway epithelium. | 30333310 |
| 2018-12-22 11:18:00 | ATP12A knockdown or inhibition prevented the IL-13 dependent increase in airway surface liquid (ASL) viscosity but did not alter the ASL pH | 29391451 |
| 2016-02-13 10:45:00 | expressing human ATP12A in cystic fibrosis mouse airways acidified airway surface liquid, impaired defenses, and increased airway bacteria. | 26823428 |
| 2015-07-04 15:17:00 | Genetic association studies show that carriers of ATP12A rs10507337 C allele or CCTTC haplotype had better pattern of myocardial relaxation as compared to non-carriers. | 25366262 |
| 2012-04-14 10:48:00 | No significantly different expression levels could be detected in the various disease states compared to normal tissue. | 22179016 |
| Type | IDs |
|---|---|
| Synonymous | ATP1AL1, HK |
| Gene |
UniProtKB-ID:
AT12A_HUMAN,
B4E0R9_HUMAN
UniprotKB:
P54707,
B4E0R9
UniParc:
UPI000016B154,
UPI000006D1DE,
UPI00017A836E
EMBL:
L42567,
L42566,
L42561,
L42563,
BC031609,
L42558,
L42559,
AL157364,
X69824,
AK303498,
U02076,
CH471075,
AK292968,
L42565,
M27574,
L42560,
L42568,
X69823,
M16797,
L42569,
L42562
Ensembl:
ENSG00000075673
KO:
hsa:479
|
| Nucleutide sequences |
EMBL-CDS:
EAX08346.1,
AAH31609.1,
EAX08345.1,
CAA49478.1,
AAA35576.1,
AAC37589.2,
AAA51802.1,
AAB37755.1,
BAF85657.1,
CAA49477.1,
BAG64531.1
Ensembl_TRS:
ENST00000381946,
ENST00000218548
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000218548,
ENSP00000371372
RefSeq:
NP_001667.4,
NP_001172014.1
|
| Others |
UniRef100:
UniRef100_B4E0R9,
UniRef100_P54707
UniRef90:
UniRef90_P54707,
UniRef90_B4E0R9
UniRef50:
UniRef50_B4E0R9,
UniRef50_P13607-7
UniGene:
Hs.147111
CCDS:
CCDS31948.1,
CCDS53858.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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