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4783 NFIL3

4783

NFIL3

nuclear factor, interleukin 3 regulated

protein-coding

Homo sapiens

基因描述

Type Description
Definition nuclear factor, interleukin 3 regulated

研究结论

Date Results Publications
2021-02-06 13:53:00 E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases. 32191636
2020-05-16 11:41:00 NFIL3 is highly expressed in osteosarcoma tissues and thus promotes the proliferation, migration, and invasion of osteosarcoma cells. NFIL3 is potential to become a new target for development of novel treatment strategies of osteosarcoma. 31886210
2020-04-18 12:40:00 our observations suggest that the NFIL3/PrPc axis, through regulating lamellipodium formation and cell mobility via JNK signaling, plays a critical role in lung cancer invasiveness and metastasis. 31477838
2019-12-14 11:50:00 Depletion of E4BP4 inhibits cancer growth, reduces hepcidin secretion, and reduces G9a nuclear transportation. Iron homeostasis and tumor growth in thyroid cancer may be regulated by an E4BP4-dependent epigenetic mechanism. 30250199
2019-09-28 11:28:00 We propose that E4BP4, being the critical component for the regulation of the above signaling processes, may serve as a novel therapeutic target for Heart failure , and scientific investigations are merited in this direction. 29856483

名称对应

Type IDs
Synonymous E4BP4, IL3BP1, NF-IL3A, NFIL3A
Gene
UniProtKB-ID: NFIL3_HUMAN, A0A024R241_HUMAN
UniprotKB: Q16649, A0A024R241
UniParc: UPI000006F28D
EMBL: CR542049, U26173, S79880, X64318, CH471089, BC008197, AL353764, AK313970, EF028070
Ensembl: ENSG00000165030
KO: hsa:4783
Nucleutide sequences
EMBL-CDS: ABK15691.1, CAG46846.1, AAA93067.1, CAA45597.1, EAW62796.1, AAH08197.1, BAG36685.1, AAB35410.1, EAW62797.1
Gene_ORFName: hCG_30387
Ensembl_TRS: ENST00000297689
Protein sequencees
Ensembl_PRO: ENSP00000297689
RefSeq: NP_001276929.1, XP_016870232.1, XP_016870233.1, NP_001276928.1, NP_005375.2
Others
UniRef100: UniRef100_Q16649
UniRef90: UniRef90_Q16649
UniRef50: UniRef50_Q16649
UniGene: Hs.79334
CCDS: CCDS6690.1

全选

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研究热度

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