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4778 NFE2

4778

NFE2

nuclear factor, erythroid 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition nuclear factor, erythroid 2

研究结论

Date Results Publications
2020-12-12 13:22:00 The transcription factor NFE2 enhances expression of the hematopoietic master regulators SCL/TAL1 and GATA2. 32593672
2020-05-16 10:42:00 data confirm that NFE2 mutations are rare, heterogenous mutations with a prevalence of frameshift and deletion, and are slightly enriched in PV. 31659782
2020-01-18 12:10:00 The NFE2-miR-423-5p-TFF1 axis is a novel molecular mechanism and provides a new direction for the study and treatment of diabetic retinopathy. 31455213
2019-12-28 10:51:00 mutations in NFE2 predispose to the acquisition of secondary changes promoting the development of myelosarcoma and/or AML 30755419
2019-09-14 10:20:00 We detected that cigarette smoke significantly increased p45 NFE2 levels in DJ-1 KO mice compared to wild-type mice. Our results indicate that p45 NFE2 expression is induced by exposure to cigarette smoke, has a cytoprotective activity against cell injury, and its downregulation in human primary ATII cells may contribute to emphysema pathogenesis 29476075

名称对应

Type IDs
Synonymous NF-E2, p45
Gene
UniProtKB-ID: NFE2_HUMAN, A8K3E0_HUMAN
UniprotKB: Q16621, A8K3E0
UniParc: UPI000012FFBA
EMBL: AK313207, L13974, AK290564, DQ367844, CR450284, AK290555, CH471054, BC005044, BT007288, L24122, S77763
Ensembl: ENSG00000123405
KO: hsa:4778
Nucleutide sequences
EMBL-CDS: AAA16118.1, AAP35952.1, AAB34115.1, AAH05044.1, CAG29280.1, ABC79302.1, AAA35612.1, EAW96772.1, BAF83253.1, BAF83244.1, BAG36023.1, EAW96771.1
Gene_ORFName: hCG_37258
Ensembl_TRS: ENST00000435572, ENST00000312156, ENST00000540264, ENST00000553070
Protein sequencees
Ensembl_PRO: ENSP00000397185, ENSP00000312436, ENSP00000447558, ENSP00000439120
RefSeq: NP_001248390.1, NP_001129495.1, NP_006154.1
Others
UniRef100: UniRef100_Q16621
UniRef90: UniRef90_Q16621
UniRef50: UniRef50_Q16621
UniGene: Hs.75643
CCDS: CCDS8876.1

全选

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