| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-10-14 12:12:00 | These observations indicate that the individual activation of ERK2 and JNK1 pathways contributes to TNF-alpha-induced IL-8 expression in synovial fibroblasts. | 28806729 |
| 2015-08-01 10:53:00 | inhibition of NCX1 by KB-R7943 in Madin-Darby canine kidney cells, LLC-PK1, and human primary renal epithelial cells (HREpiC) increased ERK1/2 activation and cell migration. | 25770213 |
| 2014-10-18 12:23:00 | These results suggested that extracellular high glucose stimulated NHE-1 acutely and chronically through Mek/Erk1/2/p90(RSK) and p38MAPK pathways, respectively. | 24557342 |
| 2014-03-29 10:13:00 | This is the first study to demonstrate that hydrogen peroxide and an inhibitor of ERK1/2 activation can increase the levels of the iron storage protein, ferritin. | 24146543 |
| 2010-01-21 00:00:00 | Activation of caspase-8 contributes to and results in confluent cell death, whereas elevated p-Erk activity serves to prevent confluent cell death by regulating activation of caspase-8. | 17219412 |
| Type | IDs |
|---|---|
| Synonymous | ERK2 |
| Gene |
UniProtKB-ID:
E2R2N2_CANLF
UniprotKB:
E2R2N2
UniParc:
UPI000000104F
EMBL:
AAEX03014899,
AAEX03014900
Ensembl:
ENSCAFG00000015421
KO:
cfa:477575
|
| Nucleutide sequences |
Ensembl_TRS:
ENSCAFT00000035708
|
| Protein sequencees |
Ensembl_PRO:
ENSCAFP00000030998
RefSeq:
NP_001104270.1
|
| Others |
UniRef100:
UniRef100_P28482
UniRef90:
UniRef90_P28482
UniRef50:
UniRef50_P28482
UniGene:
Cfa.2796
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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