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47594 aPKC

47594

aPKC

atypical protein kinase C

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition atypical protein kinase C

研究结论

Date Results Publications
2021-03-20 13:31:00 A polybasic domain in mediates Par6-dependent control of membrane targeting and kinase activity. 32580209
2019-09-14 11:49:00 helps to sharpen the pattern of Miranda, by keeping it off the apical and lateral cortex after nuclear envelope breakdown. 30635282
2018-09-01 12:06:00 Therefore, phosphorylation of Miranda by and differential binding to the actomyosin network are required at distinct phases of the cell cycle to polarize fate determinant localization in neuroblasts. 29364113
2018-08-18 11:41:00 Here we show that PTEN mutation impacts and Lgl protein levels also in Drosophila. Moreover, we demonstrate that PI3K activation is not sufficient to trigger tumourigenesis, while aduanyu1531 promotes hyperplastic growth of the neuroepithelium and a noticeable expansion of the type II neuroblasts. 29445734
2018-07-07 11:27:00 The authors find that the tumor suppressor Discs large (Dlg) links the Par complex component atypical C to the essential spindle orientation factor GukHolder (GukH). 29185419

名称对应

Type IDs
Synonymous CG10261, CG30475, CG42783, DaPKC, Dmel\CG42783, Dmel_CG10261, Dmel_CG30475, PKCl, PKCzeta, a-PKC, aPKC-zeta, aPKCzeta, aPkc, alphaPKCzeta, apkc, daPKC, dapkc, i, l(2)k06403, pkc-3, psu
Gene
UniProtKB-ID: APKC_DROME, A0A0B4KG15_DROME, A0A0B4KFQ6_DROME, A0A0B4KEQ8_DROME, A0A0B4JD78_DROME, A0A0B4JD26_DROME, A0A0B4KEV2_DROME
UniprotKB: A1Z9X0, A0A0B4KG15, A0A0B4KFQ6, A0A0B4KEQ8, A0A0B4JD78, A0A0B4JD26, A0A0B4KEV2
UniParc: UPI0000DF03DF, UPI0001F77083, UPI0000075113, UPI0000DF03DE, UPI0000DF03E0, UPI0002940E8A, UPI000293F606, UPI00004C4FBE, UPI000293FDEF, UPI0001F77085, UPI000293F839
EMBL: AE013599, AF288482, BT056247, AY118402
EnsemblGenome: FBgn0261854
KO: dme:Dmel_CG42783
Nucleutide sequences
EMBL-CDS: ABI31093.1, ABI31092.1, ABI31091.1, AAF58177.2, ABI31090.1, ACL68694.1, ABI31094.1, AAG01528.1, AAM48431.1, AGB93516.1, AGB93517.1, AGB93519.1, ADV37185.1, ADV37187.1, AGB93518.1
Gene_ORFName: CG30475, CG42783, Dmel_CG42783, CG42783, Dmel_CG42783, CG42783, Dmel_CG42783, CG42783, Dmel_CG42783, CG42783, Dmel_CG42783, CG42783, Dmel_CG42783
EnsemblGenome_TRS: FBtr0303429, FBtr0303430, FBtr0303431, FBtr0303432, FBtr0303433, FBtr0303434, FBtr0329887, FBtr0329888, FBtr0329890, FBtr0303435, FBtr0303437, FBtr0329889
Protein sequencees
EnsemblGenome_PRO: FBpp0292489, FBpp0292491, FBpp0292487, FBpp0292486, FBpp0292488, FBpp0292490, FBpp0302921, FBpp0302922, FBpp0302924, FBpp0292492, FBpp0292494, FBpp0302923
RefSeq: NP_524892.2, NP_001036545.1, NP_001036542.1, NP_001036544.1, NP_001260987.1, NP_001036543.1, NP_001260984.1, NP_001188939.1, NP_001188941.1, NP_001260986.1, NP_001036541.1, NP_001260985.1
Others
UniRef100: UniRef100_A0A0B4KFQ6, UniRef100_A1Z9X0, UniRef100_A0A0B4KEQ8, UniRef100_A0A0B4KG15, UniRef100_A0A0B4JD78, UniRef100_A0A0B4KEV2, UniRef100_A0A0B4JD26
UniRef90: UniRef90_A0A0B4KG15, UniRef90_A0A0B4JD78, UniRef90_A0A0B4JD26, UniRef90_A1Z9X0-4, UniRef90_A1Z9X0
UniRef50: UniRef50_A0A218UQ68, UniRef50_A1Z9X0, UniRef50_A0A0B4KG15
UniGene: Dm.1507

全选

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