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4752 NEK3

4752

NEK3

NIMA related kinase 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition NIMA related kinase 3

研究结论

Date Results Publications
2020-06-20 10:25:00 the NEK protein kinases emerge as important proteins in thyroid cancer development and may help to identify malignancy and aggressiveness features during diagnosis. 31906878
2018-05-12 10:33:00 NEK3 kinase phosphorylates SNAP29 on its serine 105. NEK3-mediated phosphorylation determines membrane localization of SNAP29. Membrane-associated SNAP29 regulates Golgi and focal adhesion structures. 29454964
2018-03-17 10:35:00 The data demonstrate that NEK3 is overexpressed in gastric cancer, which promotes the malignancy of gastric cancer 29504992
2017-05-20 10:50:00 these data support a modulatory role for phosphorylation at NEK3 Thr-165 in focal adhesion maturation and/or turnover to promote breast cancer cell migration. 27489110
2011-11-26 11:25:00 EHD2 interacts with Nek3 [NIMA (never in mitosis in Aspergillus nidulans)-related kinase 3], a serine/threonine kinase. 21756249

名称对应

Type IDs
Synonymous HSPK36
Gene
UniProtKB-ID: NEK3_HUMAN, Q6ZN64_HUMAN
UniprotKB: P51956, Q6ZN64
UniParc: UPI000035E78E, UPI0000E59B02, UPI000012FF28
EMBL: CH471075, AK290259, AB072828, Z29067, Z25434, AK131359, AL139082, BC019916
Ensembl: ENSG00000136098
KO: hsa:4752
Nucleutide sequences
EMBL-CDS: AAH19916.2, CAA80921.1, EAX08907.1, BAC15599.1, BAF82948.1, CAA82310.1, BAD18511.1, EAX08905.1
Gene_ORFName: hCG_29120
Ensembl_TRS: ENST00000611833, ENST00000610828, ENST00000618534
Protein sequencees
Ensembl_PRO: ENSP00000480328, ENSP00000484086, ENSP00000484443
RefSeq: NP_001139571.1, NP_689933.1, NP_002489.1
Others
UniRef100: UniRef100_P51956, UniRef100_Q6ZN64
UniRef90: UniRef90_P51956
UniRef50: UniRef50_P51956
UniGene: Hs.409989
CCDS: CCDS73576.1

全选

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