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47384 sra

47384

sra

sarah

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition sarah

研究结论

Date Results Publications
2018-10-13 11:45:00 Data suggest that sra negatively regulates calcineurin by cell-autonomously titrating calcineurin-dependent stabilization of PER and TIM proteins, thereby sustaining high-amplitude behavioral rhythms in Drosophila. 29724861
2016-12-17 10:51:00 sra overexpression augments Abeta42 cytotoxicity in Drosophila. 26659252
2014-03-22 10:04:00 Our data further suggest that upregulation of Nebula/DSCR1 is neuroprotective in the presence of APP upregulation and provides evidence for calcineurin inhibition as a novel target for therapeutic intervention of Alzheimer's disease . 24086147
2012-07-14 10:33:00 findings suggest a mechanism in which Shaggy/GSK-3beta activates calcineurin through Sarah phosphorylation on egg activation in Drosophila 22421435
2011-11-05 11:11:00 Calcineurin and its regulation by Sra are required for normal sleep in Drosophila 21900555

名称对应

Type IDs
Synonymous 89B, 89B11, CG6072, Dmel\CG6072, Sra, anon-WO0118547.92, anon-WO0172774.10, l(3)05203, nebula, nla
Gene
UniProtKB-ID: SRA_DROME, A0A0B4LHI3_DROME
UniprotKB: Q9XZL8, A0A0B4LHI3
UniParc: UPI00001248A3
EMBL: AE014297, AY061194, AF147700
EnsemblGenome: FBgn0086370
KO: dme:Dmel_CG6072
Nucleutide sequences
EMBL-CDS: AAD33987.1, AAF55285.1, AAL28742.1, AHN57360.1
Gene_ORFName: CG6072, Dmel_CG6072, CG6072
EnsemblGenome_TRS: FBtr0083255, FBtr0344473, FBtr0083255, FBtr0344473
Protein sequencees
EnsemblGenome_PRO: FBpp0310844, FBpp0082709, FBpp0310844, FBpp0082709
RefSeq: NP_524378.1, NP_001287361.1
Others
UniRef100: UniRef100_Q9XZL8
UniRef90: UniRef90_Q9XZL8
UniRef50: UniRef50_Q9XZL8
UniGene: Dm.1655

全选

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研究热度

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