| Type | Description |
|---|---|
| Definition | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:24:00 | Auto-ubiquitination of NEDD4-1 Recruits USP13 to Facilitate Autophagy through Deubiquitinating VPS34. | 32101753 |
| 2021-02-20 13:30:00 | PRRG4 promotes breast cancer metastasis through the recruitment of NEDD4 and downregulation of Robo1. | 33037408 |
| 2020-10-31 13:16:00 | Binding site plasticity in viral PPxY Late domain recognition by the third WW domain of human NEDD4. | 31636332 |
| 2020-10-24 14:06:00 | PPARgamma induces NEDD4 gene expression to promote autophagy and insulin action. | 31423749 |
| 2020-08-15 19:04:00 | Distinguishing the optimal binding mechanism of an E3 ubiquitin ligase: Covalent versus noncovalent inhibition. | 30854719 |
| Type | IDs |
|---|---|
| Synonymous | NEDD4-1, RPF1 |
| Gene |
UniProtKB-ID:
NEDD4_HUMAN
UniprotKB:
P46934
UniParc:
UPI00001FE52D,
UPI000189A81E,
UPI00001418FE,
UPI00001C1F92
EMBL:
BC144285,
BC144284,
D42055,
AY550969,
AC039057,
BC136605,
BC152452,
AC009997,
CH471082,
BC152562,
AK304394,
AL832063
Ensembl:
ENSG00000069869
KO:
hsa:4734
|
| Nucleutide sequences |
EMBL-CDS:
AAI44285.1,
AAT52215.1,
BAG65229.1,
AAI36606.1,
AAI44286.1,
AAI52453.1,
BAA07655.1,
EAW77495.1,
AAI52563.1
Gene_ORFName:
PIG53
Ensembl_TRS:
ENST00000508342,
ENST00000506154,
ENST00000435532,
ENST00000338963
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000345530,
ENSP00000424827,
ENSP00000410613,
ENSP00000422705
RefSeq:
NP_001271268.1,
NP_001271267.1,
NP_006145.2,
XP_011519926.1,
XP_011519928.1,
XP_011519927.1,
NP_001316141.1,
NP_001271269.1,
NP_940682.2
|
| Others |
UniRef100:
UniRef100_P46934
UniRef90:
UniRef90_P46934
UniRef50:
UniRef50_P46934
UniGene:
Hs.1565
CCDS:
CCDS45265.1,
CCDS10156.1,
CCDS61644.1,
CCDS61643.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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