| Type | Description |
|---|---|
| Definition | developmentally regulated GTP binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:30:00 | m6A-dependent up-regulation of DRG1 by METTL3 and ELAVL1 promotes growth, migration, and colony formation in osteosarcoma. | 32266933 |
| 2019-04-27 11:11:00 | In vitro, DRG1 can diffuse on microtubules, promote their polymerization, drive microtubule formation into bundles, and stabilize microtubules. HeLa cells with reduced DRG1 levels show delayed progression from prophase to anaphase because spindle formation is slowed down. | 28855639 |
| 2018-03-03 11:55:00 | DRG1 was an important protein involved in spindle checkpoint signaling, and elevated levels of DRG1 caused lung adenocarcinoma and taxol resistance. | 27626498 |
| 2016-02-20 11:23:00 | DRG-1 plays an important role in melanoma cell growth and transformation, indicating that DRG1 may represent a novel target for CD4(+) T cell-mediated immunotherapy in melanoma. | 25993655 |
| 2013-09-28 11:20:00 | Lerepo4 action leaves Drg1 affinity for nucleotides unaffected, feasibly favoring a switch I reorientation, mainly via the TGS domain. | 23711155 |
| Type | IDs |
|---|---|
| Synonymous | NEDD3 |
| Gene |
UniProtKB-ID:
DRG1_HUMAN
UniprotKB:
Q9Y295
UniParc:
UPI0000129879
EMBL:
CR542059,
AL096701,
AJ005940,
AK315659,
AL096702,
BC020803,
BT007237,
CR456488,
BC019285,
CH471095,
AF078103
Ensembl:
ENSG00000185721
KO:
hsa:4733
|
| Nucleutide sequences |
EMBL-CDS:
BAG38025.1,
CAA06775.1,
AAH19285.1,
CAG46856.1,
AAH20803.1,
EAW59976.1,
AAD12240.1,
AAP35901.1,
CAG30374.1
Ensembl_TRS:
ENST00000331457
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000329715
RefSeq:
NP_004138.1
|
| Others |
UniRef100:
UniRef100_Q9Y295
UniRef90:
UniRef90_Q9Y295
UniRef50:
UniRef50_Q9Y295
UniGene:
Hs.115242
CCDS:
CCDS13897.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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