| Type | Description |
|---|---|
| Definition | NADH:ubiquinone oxidoreductase subunit C2 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-15 10:10:00 | A significant reduction of NDUFC2 expression is detected in ACS. In vitro, NDUFC2 silencing affects vascular cell viability and angiogenesis while stimulating the expression of markers of plaque rupture. Our observations suggest that these mechanisms may contribute to ACS development. | 30808603 |
| 2018-05-26 11:11:00 | Authors found that both fibroblasts obtained from skin of heterozygous Ndufc2 knock-out rat model showed marked mitochondrial dysfunction and human PBMC homozygous for the TT genotype of the rs11237379/NDUFC2 variant, previously shown to associate with reduced gene expression, demonstrated increased generation of reactive oxygen species and mitochondrial damage. | 28973657 |
| 2017-01-14 11:13:00 | Ndufc2 SNPs can contribute to an increased occurrence of early-onset ischemic stroke in humans. | 26888427 |
| 2015-09-26 10:35:00 | Expression profiling of SCN8A and NDUFC2 genes in colorectal carcinoma is reported. There was no NDUFC2 differential expression in colorectal carcinoma. | 25804238 |
| 2013-01-26 10:21:00 | DNA methylation of genes in retinol metabolism and calcium signaling pathways (P < 3 x 10-6) and with known functions in muscle and T2D including MEF2A, RUNX1, NDUFC2, and THADA decreased after exercise | 23028138 |
| Type | IDs |
|---|---|
| Synonymous | B14.5b, CI-B14.5b, HLC-1, NADHDH2 |
| Gene |
UniProtKB-ID:
NDUC2_HUMAN,
A0A024R5K6_HUMAN
UniprotKB:
O95298,
A0A024R5K6
UniParc:
UPI0001F780F2,
UPI0000405F10,
UPI000012FC27
EMBL:
AF369951,
AF070652,
CR533448,
AL050278,
BC007323,
AP003032,
AF087899,
CH471076,
AF087659
Ensembl:
ENSG00000151366
KO:
hsa:4718
|
| Nucleutide sequences |
EMBL-CDS:
CAG38479.1,
AAP97198.1,
AAM21294.1,
AAD20958.1,
AAD09754.1,
EAW75046.1,
AAH07323.1,
CAB43379.1,
EAW75047.1
Gene_ORFName:
HLC1,
hCG_1643251
Ensembl_TRS:
ENST00000281031,
ENST00000527806,
ENST00000525085
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000281031,
ENSP00000432739,
ENSP00000434262
RefSeq:
NP_004540.1,
NP_001190984.1,
NP_001190983.1
|
| Others |
UniRef100:
UniRef100_O95298
UniRef90:
UniRef90_O95298
UniRef50:
UniRef50_O95298
UniGene:
Hs.407860
CCDS:
CCDS55779.1,
CCDS55781.1,
CCDS8257.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员