| Type | Description |
|---|---|
| Definition | nucleolin |
| Date | Results | Publications |
|---|---|---|
| 2020-12-26 13:12:00 | Growth Factor Midkine Aggravates Pulmonary Arterial Hypertension via Surface Nucleolin. | 32587339 |
| 2020-07-11 12:15:00 | Study describes the molecular mechanism by which nucleolin (NCL) recognizes G-quadruplexes (G4)-containing long loops and leads to the proposal of a model implying a concerted action of RNA binding domain 2 (RBD2) and glycine/arginine (RGG) domains to achieve specific G4 recognition via a dual loop-quartet interaction. | 32191439 |
| 2020-05-23 10:50:00 | CSA and CSB are positive regulators of ribosomal RNA synthesis via Ncl regulation. | 31970402 |
| 2020-05-09 11:56:00 | Nucleolin expressed on the surface of head and neck squamous cell carcinoma cells is an active ligand for L-selectin. | 31644306 |
| 2020-04-11 10:46:00 | Nucleolin (NCL) is a major regulator of miR processing in response to OS and essential for the maturation of miR-93 and miR-484 that target mRNAs encoding KLF2 and eNOS. AMPK phosphorylation of NCL sequesters it in the nucleus, thereby inhibiting miR-93 and miR-484 processing and their subsequent targeting of KLF2 and eNOS mRNA. Elevated levels of miR-93 and miR-484 were found in sera of coronary artery disease patients. | 31182601 |
| Type | IDs |
|---|---|
| Synonymous | C23, Nsr1 |
| Gene |
UniProtKB-ID:
NUCL_HUMAN,
B3KM80_HUMAN
UniprotKB:
P19338,
B3KM80
UniParc:
UPI000015F311,
UPI0000456F25
EMBL:
CH471063,
M60858,
AK001314,
AC017104,
AK091742
Ensembl:
ENSG00000115053
KO:
hsa:4691
|
| Nucleutide sequences |
EMBL-CDS:
AAY24247.1,
AAA59954.1,
BAC03738.1,
EAW70962.1,
BAG50892.1
Gene_ORFName:
hCG_33980
Ensembl_TRS:
ENST00000322723
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000318195
RefSeq:
NP_005372.2
|
| Others |
UniRef100:
UniRef100_P19338
UniRef90:
UniRef90_P19338
UniRef50:
UniRef50_P19338
UniGene:
Hs.79110
CCDS:
CCDS33397.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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