| Type | Description |
|---|---|
| Definition | neutrophil cytosolic factor 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-28 12:03:00 | We report on 24 p40phox-deficient patients from 12 additional families in 8 countries. These patients display 8 different in-frame or out-of-frame mutations of NCF4 that are homozygous in 11 of the families and compound heterozygous in another. | 29969437 |
| 2019-03-09 12:36:00 | Tyrosine kinase substrate (Tks) proteins, analogous to the related proteins p47(phox), p40(phox) and NoxO1, also facilitate local generation of reactive oxygen species which aid in signaling at invadopodia and/or podosomes to promote their activity. As their name suggests, Tks adaptor proteins are substrates for tyrosine kinases, especially Src. [review] | 29311151 |
| 2017-09-09 13:29:00 | Phosphoinositol 3-phosphate regulates reactive oxygen species production by maintaining p40phox and p67phox at the phagosomal membrane. | 28096301 |
| 2016-06-28 11:19:00 | NCF4 polymorphism was associated with Crohn's disease, but not ulcerative colitis in Caucasian--{REVIEW} | 26289093 |
| 2014-09-27 11:03:00 | NCF4 may induce ex- pression of NADPH oxidase enzymes, such as p67phox, p47phox, p22phox and NOX2, which lead to increased levels. | 24378533 |
| Type | IDs |
|---|---|
| Synonymous | CGD3, NCF, P40PHOX, SH3PXD4 |
| Gene |
UniProtKB-ID:
NCF4_HUMAN,
A0A494BZS1_HUMAN
UniprotKB:
Q15080,
A0A494BZS1
UniParc:
UPI0007DC832C,
UPI000013CC59,
UPI0000049C2C
EMBL:
AL008637,
U50721,
U50726,
U50722,
U50723,
U50724,
CR456528,
AB025220,
U50728,
BT007346,
AK290924,
U50725,
U50729,
BC002798,
U50727,
X77094,
DQ314880,
U50720,
AB025219
Ensembl:
ENSG00000100365
KO:
hsa:4689
|
| Nucleutide sequences |
EMBL-CDS:
AAH02798.1,
BAA89791.1,
AAB39970.1,
BAA89792.1,
CAG30414.1,
BAF83613.1,
AAP36010.1,
ABC40739.1,
CAA54372.1
Ensembl_TRS:
ENST00000248899,
ENST00000397147,
ENST00000650698,
ENST00000650827
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000248899,
ENSP00000380334,
ENSP00000498381,
ENSP00000498212
RefSeq:
NP_038202.2,
NP_000622.2,
XP_016884297.1
|
| Others |
UniRef100:
UniRef100_Q15080
UniRef90:
UniRef90_Q15080
UniRef50:
UniRef50_Q15080
UniGene:
Hs.474781
CCDS:
CCDS13935.1,
CCDS13934.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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