| Type | Description |
|---|---|
| Definition | NBL1, DAN family BMP antagonist |
| Date | Results | Publications |
|---|---|---|
| 2017-11-18 13:45:00 | The structure of Grem2-GDF5 complex has revealed a number of key findings for DAN-family mediated BMP2 inhibition. | 27524626 |
| 2015-05-09 12:18:00 | inhibition toward BMP2 and BMP7, but not GDF5. Although NBL1(S67Y) was able to antagonize BMP7 as effectively as PRDC, NBL1(S67Y) was still 32-fold weaker than PRDC against BMP2. | 25561725 |
| 2015-04-25 12:12:00 | The DAN family proteins with regards to BMP inhibition and also highlights their emerging roles in the modulation of Wnt and VEGF signaling pathways. | 24810382 |
| 2014-08-30 11:01:00 | NBL1 is a secreted protein that is highly restricted to the prostate. Underexpression of NBL1 correlated with prostate cancer progression. | 22948749 |
| 2011-12-31 10:40:00 | CDKN2A, GATA3, CREBBP, ITGA2, NBL1 and TGM4 were down-regulated in the prostate carcinoma glands compared to the corresponding normal glands | 21743959 |
| Type | IDs |
|---|---|
| Synonymous | D1S1733E, DAN, DAND1, NB, NO3 |
| Gene |
UniProtKB-ID:
NBL1_HUMAN,
A0A087WTY6_HUMAN
UniprotKB:
P41271,
A0A087WTY6
UniParc:
UPI0001892A52,
UPI0000071C54,
UPI000020459F
EMBL:
KF510717,
BT019423,
AK313265,
AK289456,
AY049783,
AL031727,
D28124,
BC012037,
AK292101,
AK300872,
CH471134,
D89013
Ensembl:
ENSG00000158747
KO:
hsa:100532736,
hsa:4681
|
| Nucleutide sequences |
EMBL-CDS:
BAF84790.1,
EAW94895.1,
AAH12037.1,
BAA92265.1,
AAL15440.1,
BAA05671.1,
BAG36074.1,
BAF82145.1,
BAG62517.1,
EAW94894.1,
AAV38230.1
Ensembl_TRS:
ENST00000548815,
ENST00000621723,
ENST00000375136,
ENST00000618761,
ENST00000289749,
ENST00000622566,
ENST00000602662,
ENST00000615215
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000483061,
ENSP00000364278,
ENSP00000449007,
ENSP00000478885,
ENSP00000289749,
ENSP00000480391,
ENSP00000473411,
ENSP00000478223
RefSeq:
NP_001265093.1,
NP_877421.2,
NP_001191013.1,
NP_001191014.1,
NP_001265095.1,
NP_005371.2,
NP_001191015.1,
NP_001265094.1
|
| Others |
UniRef100:
UniRef100_A0A087WTY6,
UniRef100_P41271
UniRef90:
UniRef90_A0A2K5J2N7,
UniRef90_P41271
UniRef50:
UniRef50_P41271
UniGene:
Hs.654502
CCDS:
CCDS196.2,
CCDS41278.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员