| Type | Description |
|---|---|
| Definition | nuclear autoantigenic sperm protein |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 12:26:00 | miR-381-3p targeted and suppressed NASP gene, reduced the viability, migration, invasion, EMT of HNSCC cells, demonstrating that miR-381-3p has the potential to be a therapeutic target in inhibiting the progression of HNSCC | 31797734 |
| 2019-05-25 11:51:00 | Results found that NASP expression levels were upregulated in liver tumors. Its down-regulation inhibited liver cells from forming tumors. Also, NASP depletion led to a global decrease of histone H3K9me1 modification associated with newly H3 processing, which occurred directly at the promoters of up-regulated anti-tumor genes BACH2 and RunX1T1. | 30076957 |
| 2018-03-31 12:18:00 | NASP is targeted by miR-29c in gastric cancer cells. miR-29c can decrease NASP expression and the effects observed following miR-29c overexpression are partially due to NASP depletion. | 28173777 |
| 2016-09-24 11:26:00 | findings reveal a new mode of interaction between a TPR repeat domain of histone chaperone sNASP and an evolutionarily conserved peptide motif found in canonical H3 and in all histone H3 variants | 26673727 |
| 2015-10-31 10:10:00 | Our research demonstrates that knockdown of tNASP effectively inhibits the proliferation and causes G1 phase arrest through ERK/MAPK signal pathway. | 25669170 |
| Type | IDs |
|---|---|
| Synonymous | FLB7527, HMDRA1, PRO1999 |
| Gene |
UniProtKB-ID:
NASP_HUMAN,
Q5T626_HUMAN
UniprotKB:
P49321,
Q5T626
UniParc:
UPI000002AED8,
UPI000012FDA0,
UPI0001E1129F,
UPI000016783C
EMBL:
BT006757,
BC003113,
BC011580,
CH471059,
AK056161,
M97856,
BC053608,
BC010105,
AK222816,
AL355480,
AK298893,
AK291637
Ensembl:
ENSG00000132780
KO:
hsa:4678
|
| Nucleutide sequences |
EMBL-CDS:
BAF84326.1,
BAD96536.1,
EAX06968.1,
EAX06969.1,
AAH03113.1,
AAH10105.1,
AAH11580.1,
AAH53608.1,
BAG61005.1,
AAA36027.1,
EAX06965.1,
EAX06964.1,
AAP35403.1
Gene_ORFName:
hCG_40880
Ensembl_TRS:
ENST00000351223,
ENST00000537798,
ENST00000350030
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000255120,
ENSP00000438871,
ENSP00000255121
RefSeq:
XP_005270945.1,
XP_005270946.1,
XP_016856845.1,
NP_002473.2,
NP_001182122.1,
XP_011539811.1,
NP_689511.2
|
| Others |
UniRef100:
UniRef100_P49321,
UniRef100_Q5T626
UniRef90:
UniRef90_P49321,
UniRef90_A0A0D9S7F7
UniRef50:
UniRef50_A0A0D9S7F7,
UniRef50_P49321
UniGene:
Hs.319334
CCDS:
CCDS524.1,
CCDS55597.1,
CCDS525.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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