| Type | Description |
|---|---|
| Definition | NLR family apoptosis inhibitory protein |
| Date | Results | Publications |
|---|---|---|
| 2020-02-22 12:56:00 | Results suggest that that the copy number variance of SMN2 and NAIP is correlated with the spinal muscular atrophy (SMA) phenotype in 40 patients. The copy number of SMN2 and NAIP gene had synergistic effect on SMA phenotype. Analysis of the copy number structure of the SMN1-SMN2-NAIP gene is helpful for SMA typing, disease prognosis prediction, and genetic counseling. | 32011487 |
| 2018-11-24 10:05:00 | Our present report implies that NAIP will have broad implications for ALS symptoms as a risk factor and a promising prognostic biomarker. | 29311650 |
| 2018-11-03 11:05:00 | Data document a previously unknown localization of NAIP along the entire cytokinetic process whose dynamics exhibits a distinct behavior. | 28059125 |
| 2018-06-30 12:13:00 | NAIP expression is most abundant in M2 macrophages, while cIAP1 and cIAP2 show an inverse pattern of expression in polarized cells, cIAP2 is preferentially expressed in M1-macrophages and cIAP1 in M2-macrophages. IAP antagonist treatment of resting M0 macrophages preceding polarization stimulation, induced upregulation of NAIP in M2 and downregulation of cIAP1 in M1 and M2 but an induction of cIAP2 in M1 macrophages. | 29518103 |
| 2017-03-04 11:21:00 | Deletion in NAIP gene is associated with spinal muscular atrophy. | 27754957 |
| Type | IDs |
|---|---|
| Synonymous | BIRC1, NLRB1, psiNAIP |
| Gene |
UniProtKB-ID:
BIRC1_HUMAN
UniprotKB:
Q13075
UniParc:
UPI000013C609,
UPI000020C371
EMBL:
AC044797,
AC005031,
AB209123,
U80017,
U19251,
BC136273,
AB048534,
AH003063
Ensembl:
ENSG00000278613,
ENSG00000249437
KO:
hsa:4671
|
| Nucleutide sequences |
EMBL-CDS:
AAC62261.1,
BAD92360.1,
BAB87181.1,
AAC52045.1,
AAC52047.1,
AAI36274.1,
AAA64504.1
Ensembl_TRS:
ENST00000194097,
ENST00000523981,
ENST00000517649,
ENST00000620988,
ENST00000503719,
ENST00000612328
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000484107,
ENSP00000424913,
ENSP00000443944,
ENSP00000484731,
ENSP00000428363,
ENSP00000428657
RefSeq:
NP_075043.1,
NP_001333799.1,
NP_004527.2
|
| Others |
UniRef100:
UniRef100_Q13075
UniRef90:
UniRef90_Q13075
UniRef50:
UniRef50_Q13075
UniGene:
Hs.654500,
Hs.710305
CCDS:
CCDS43327.1,
CCDS4009.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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