| Type | Description |
|---|---|
| Definition | nascent polypeptide associated complex subunit alpha |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 11:41:00 | These results suggest that PP1A dephosphorylates NACA at specific residues, impacting cJUN transcriptional activity and osteoblast differentiation and function. | 30948508 |
| 2019-10-19 11:52:00 | NAC is a potent suppressor of aggregation and proteotoxicity of mutant PolyQ-expanded proteins associated with human diseases like Huntington's disease and spinocerebellar ataxias. | 30982745 |
| 2015-02-14 13:40:00 | depletion of alphaNAC in multiple types of cancer cells induce typical apoptotic cell death. This anti-apoptotic function is mediated by the FADD/c-Jun N-terminal kinase pathway. | 24901053 |
| 2015-02-14 12:37:00 | Low NACA expression is associated with rhabdomyosarcoma. | 25209525 |
| 2012-01-07 11:34:00 | [review] First evidence of a functional interaction between ATF4, FIAT (factor-inhibiting ATF4-mediated transcription) and alphaNAC (nascent polypeptide-associated complex and coactivator alpha). | 22082360 |
| Type | IDs |
|---|---|
| Synonymous | HSD48, NAC-alpha, NACA1, skNAC |
| Gene |
UniProtKB-ID:
NACA_HUMAN,
A0A024RB41_HUMAN
UniprotKB:
Q13765,
A0A024RB41
UniParc:
UPI0000073EC7
EMBL:
AY911673,
X80909,
AF054187,
AK090650,
BC105122,
CR450295,
AK223085,
BC105120,
AY605660,
BC106041,
AC117378,
CH471054,
AK311904,
AY034001
Ensembl:
ENSG00000196531
KO:
hsa:4666
|
| Nucleutide sequences |
EMBL-CDS:
AAX14393.1,
AAC99403.1,
CAA56869.1,
AAI06042.1,
EAW96960.1,
AAK57544.1,
CAG29291.1,
AAI05121.1,
BAG52208.1,
BAG34845.1,
AAV83778.1,
BAD96805.1,
AAI05123.1,
EAW96961.1
Gene_ORFName:
HSD48,
hCG_2016482
Ensembl_TRS:
ENST00000356769,
ENST00000393891,
ENST00000552540,
ENST00000546392
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000446801,
ENSP00000377469,
ENSP00000349212,
ENSP00000447821
RefSeq:
NP_001106673.1,
NP_001307123.1,
NP_005585.1,
NP_001307122.1,
NP_001106674.2,
NP_001352825.1,
NP_001106672.1
|
| Others |
UniRef100:
UniRef100_Q13765
UniRef90:
UniRef90_Q13765
UniRef50:
UniRef50_Q13765
UniGene:
Hs.505735
CCDS:
CCDS31837.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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