| Type | Description |
|---|---|
| Definition | myosin VB |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:28:00 | MYO5B mutations in pheochromocytoma/paraganglioma promote cancer progression. | 32511227 |
| 2020-05-30 10:46:00 | this study demonstrates the essential role of Myo5b in maintaining the epidermal barrier integrity | 30660668 |
| 2020-02-15 11:14:00 | Authors identified a novel role for MYO5B in the regulation of late endosome size control and identify the inability to control late endosome size as an unexpected novel mechanism underlying defects in cell division orientation and epithelial architecture. | 31682603 |
| 2017-12-23 10:21:00 | Data suggest that membrane tethering mediated by endosomal RAB11A is drastically and selectively stimulated by its cognate Rab effectors, class V myosins (MYO5A and MYO5B), in a GTP-dependent manner. (RAB11A = ras-related GTPase Rab-11A; MYO5 = myosin class V) | 28939769 |
| 2017-11-25 15:28:00 | Data suggest that single-headed myosin-5B is intermediate-duty ratio motor with kinetic ATPase cycle, rate-limited by phosphate release; in transition to high-duty ratio motor, second head generates strain/gating in myosin-5B dimer that alter kinetic signature by slowing actin-activated ADP release to become rate-limiting; myosin-5B mutations cause microvillus inclusion disease and impact myosin motor function. | 28882893 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MYO5B_HUMAN,
Q7Z7A5_HUMAN
UniprotKB:
Q9ULV0,
Q7Z7A5
UniParc:
UPI00000731A1,
UPI00001D7B21,
UPI00006C190A,
UPI000019B4F0
EMBL:
AC090227,
AB290160,
AC105224,
BC033527,
AC092705,
AK025336,
AC091044,
AY274809,
AB032945
Ensembl:
ENSG00000167306
KO:
hsa:4645
|
| Nucleutide sequences |
EMBL-CDS:
AAH33527.1,
BAA86433.2,
BAG06714.1,
BAB15114.1,
AAP42074.1
Ensembl_TRS:
ENST00000285039,
ENST00000592688
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000285039,
ENSP00000466368
RefSeq:
NP_001073936.1
|
| Others |
UniRef100:
UniRef100_Q7Z7A5,
UniRef100_Q9ULV0
UniRef90:
UniRef90_Q7Z7A5,
UniRef90_Q9ULV0
UniRef50:
UniRef50_A0A3P9MJ39,
UniRef50_Q9ULV0
UniGene:
Hs.720076
CCDS:
CCDS42436.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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