| Type | Description |
|---|---|
| Definition | myosin VA |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:31:00 | LUZP1 and the tumor suppressor EPLIN modulate actin stability to restrict primary cilia formation. | 32496561 |
| 2020-02-22 10:06:00 | Spermine synthase (SMS) localized together with myosin Va (MyoVa) in cytoplasmic vesicles of breast cancer MCF-7 and neuroblastoma SH-SY5Y cell lines, known to produce exosomes, supporting a role for MyoVa in SMS expression and targeting. | 30733278 |
| 2019-05-18 10:31:00 | demonstrate that high expression of myosin 5a may be an independent prognostic factor in patients with Esophageal squamous cell carcinoma | 29898384 |
| 2019-04-13 10:43:00 | Depletion of myosin-Va significantly inhibits the attachment of preciliary vesicles to the distal appendages of the mother centriole and decreases cilia assembly. Myosin-Va functions upstream of EHD1- and Rab11-mediated ciliary vesicle formation. | 29335527 |
| 2018-11-10 10:31:00 | our studies revealed RPGRIP1L as a novel MyoVa-binding protein - the first to be demonstrated to interact with MyoVa at the centrosome - and uncover an unprecedented link between MyoVa and ciliogenesis, providing new perspectives for studies aiming to better understand why defects in MyoVa cause neurological disorders in Griscelli syndrome patients. | 28266547 |
| Type | IDs |
|---|---|
| Synonymous | GS1, MYH12, MYO5, MYR12 |
| Gene |
UniProtKB-ID:
MYO5A_HUMAN,
Q9UES4_HUMAN,
A8CDT9_HUMAN
UniprotKB:
Q9Y4I1,
Q9UES4,
A8CDT9
UniParc:
UPI0000E445E1,
UPI000006CD1A,
UPI0001AE684F,
UPI0001AE686A,
UPI00015CFC58
EMBL:
AC025917,
S74799,
U90942,
Y07759,
AC018902,
AF090426,
AF055459,
AB290180,
Z22957,
AC010674
Ensembl:
ENSG00000197535
KO:
hsa:4644
|
| Nucleutide sequences |
EMBL-CDS:
AAC14188.1,
CAA69036.1,
AAD00702.1,
AAB33211.1,
CAA69035.1,
CAA80533.1,
AAC83703.1,
BAF80583.1
Ensembl_TRS:
ENST00000356338,
ENST00000399231
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000382177,
ENSP00000348693
RefSeq:
XP_011519912.2,
NP_001369278.1,
XP_011519909.2,
NP_001369276.1,
NP_001369277.1,
XP_016877716.1,
XP_011519911.2,
XP_011519913.2,
XP_011519914.2,
NP_000250.3,
NP_001135967.2
|
| Others |
UniRef100:
UniRef100_O95317,
UniRef100_Q9Y4I1,
UniRef100_A8CDT9
UniRef90:
UniRef90_Q9Y4I1-3,
UniRef90_Q99104
UniRef50:
UniRef50_Q99104,
UniRef50_Q9Y4I1-3
UniGene:
Hs.21213,
Hs.596221
CCDS:
CCDS42037.1,
CCDS45262.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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