| Type | Description |
|---|---|
| Definition | growth arrest and DNA damage inducible beta |
| Date | Results | Publications |
|---|---|---|
| 2020-01-11 12:40:00 | We found that GADD45B is indispensable for DNA damage protection and survival in stem cells. Thus, we describe an easy and efficient protocol of DNA-free gene editing of hard-to-target transcripts and enrichment of gene-modified cells that are generally difficult to transfect. | 30622144 |
| 2019-10-05 10:35:00 | demonstrate the protective role of GADD45beta in sepsis and the results suggest that GADD45beta could be used as a novel therapeutic target to cure sepsis | 29741778 |
| 2019-02-16 11:23:00 | Down-regulation of GADD45beta can reduce the colony-forming ability of PC9 cells, promote the cell apoptosis, and enhance the sensitivity of PC9 cells to gefitinib | 30643065 |
| 2019-02-09 11:51:00 | Although GADD45B is elevated in prostate cancer tissues, levels of GADD45B in prostate tumor tissues are reduced at late stage of tumor invasion, and higher levels of GADD45B predict better survivals of prostate cancer patients. | 29356020 |
| 2019-01-19 12:35:00 | High GADD45B expression is associated with cancer. | 29279355 |
| Type | IDs |
|---|---|
| Synonymous | GADD45BETA, MYD118 |
| Gene |
UniProtKB-ID:
GA45B_HUMAN,
K7EPQ8_HUMAN
UniprotKB:
O75293,
K7EPQ8
UniParc:
UPI000012AEF0,
UPI0002840B69
EMBL:
AK293087,
AF533019,
AC005624,
AF078077,
AF090950,
CH471139,
BC113466,
BC117469,
AF087853
Ensembl:
ENSG00000099860
KO:
hsa:4616
|
| Nucleutide sequences |
EMBL-CDS:
AAM92794.1,
AAC34572.1,
AAI17470.1,
AAC36361.1,
AAG48366.1,
AAC83328.1,
AAI13467.1,
EAW69376.1,
BAF85776.1
Ensembl_TRS:
ENST00000215631,
ENST00000587345
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000215631,
ENSP00000467490
RefSeq:
NP_056490.2,
XP_016882311.1
|
| Others |
UniRef100:
UniRef100_K7EPQ8,
UniRef100_O75293
UniRef90:
UniRef90_O75293,
UniRef90_A0A2I3LH90
UniRef50:
UniRef50_Q6PC51,
UniRef50_O75293
UniGene:
Hs.110571
CCDS:
CCDS32868.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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