| Type | Description |
|---|---|
| Definition | myosin binding protein H |
| Date | Results | Publications |
|---|---|---|
| 2016-09-03 10:52:00 | variation in MYBPH can modulate the severity of hypertrophy in hypertrophic cardiomyopathy patients. | 26969327 |
| 2014-03-29 11:22:00 | MyBP-H expression signals the onset of dysregulation in actin-myosin interaction; this in turn might contribute to the pathogenesis of amyotrophic lateral sclerosis. | 24184715 |
| 2013-03-30 13:09:00 | These results suggest that MYBPH inhibits RLC and NMHC IIA, independent components of NM IIA, and negatively regulates actomyosin organization at 2 distinct steps, resulting in firm inhibition of NM IIA assembly. | 23068101 |
| 2012-03-31 11:14:00 | MYBPH inhibited assembly competence-conferring phosphorylation of the myosin regulatory light chain (RLC) as well as activating phosphorylation of LIM domain kinase, unexpectedly through its direct physical interaction with Rho kinase 1 | 22085929 |
| 2009-08-12 21:34:00 | Observational study of gene-disease association. (HuGE Navigator) | 19536175 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MYBPH_HUMAN
UniprotKB:
Q13203
UniParc:
UPI000000DA7B
EMBL:
L05606,
L05607,
BC044226,
U27266
Ensembl:
ENSG00000133055
KO:
hsa:4608
|
| Nucleutide sequences |
EMBL-CDS:
AAB86737.1,
AAA02904.2,
AAH44226.1,
AAA36339.1
Ensembl_TRS:
ENST00000255416
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000255416
RefSeq:
NP_004988.2
|
| Others |
UniRef100:
UniRef100_Q13203
UniRef90:
UniRef90_Q13203
UniRef50:
UniRef50_Q13203
UniGene:
Hs.927
CCDS:
CCDS30975.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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