| Type | Description |
|---|---|
| Definition | MAX interactor 1, dimerization protein |
| Date | Results | Publications |
|---|---|---|
| 2019-11-30 11:18:00 | HIF-1alpha-induced FOXO3a promotes apoptosis of hypoxic endothelial cells by directly inducing Mxi1- 0, which leads to the activation of caspase-8 apoptotic pathway. | 30118760 |
| 2019-01-19 11:35:00 | a phosphorylation mutant form of Mxi1 (Mxi1-S160A), which cannot be degraded by S6K1 and beta-Trcp, is much more stable and efficient in suppressing the transcriptional activity of Myc and radioresistance in lung cancer cells. | 29507620 |
| 2017-12-02 10:58:00 | Reactive oxygen species mediates hypoxia-induced VEGF by upregulation of Mxi1-0. | 28065785 |
| 2017-09-23 10:17:00 | results suggest that Mxi1-0 regulates the growth of HUVECs via the IL-8 and ERK1/2 pathways, which apparently reciprocally activate each other | 28575053 |
| 2014-12-06 11:27:00 | MYC-HEG and MXI1-LEG levels are associated with poor prognosis in patients with breast cancer, suggesting that they may be useful molecular markers in breast cancer prognosis prediction. | 24685915 |
| Type | IDs |
|---|---|
| Synonymous | MAD2, MXD2, MXI, bHLHc11 |
| Gene |
UniProtKB-ID:
MXI1_HUMAN,
A0A0S2Z3X5_HUMAN
UniprotKB:
P50539,
A0A0S2Z3X5
UniParc:
UPI000013CA6C,
UPI000016AA71,
UPI0000376B16,
UPI0000071BF5
EMBL:
U32515,
KU178207,
BC012907,
BT007069,
BC035128,
S78470,
AL360182,
U32512,
U32514,
U32513,
CR536576,
L07648,
CH471066,
D63940
Ensembl:
ENSG00000119950
KO:
hsa:4601
|
| Nucleutide sequences |
EMBL-CDS:
AAH35128.2,
EAW49568.1,
AAD14282.1,
EAW49570.1,
EAW49569.1,
AAC50446.1,
CAG38813.1,
EAW49565.1,
AAP35732.1,
AAH12907.1,
EAW49567.1,
AAA75508.1,
BAA09972.1,
ALQ33665.1
Ensembl_TRS:
ENST00000651613,
ENST00000651866,
ENST00000361248,
ENST00000651167,
ENST00000650952,
ENST00000652604,
ENST00000650810,
ENST00000369612,
ENST00000652463,
ENST00000652506,
ENST00000332674,
ENST00000652028,
ENST00000651004,
ENST00000651848,
ENST00000650843,
ENST00000651811,
ENST00000650644,
ENST00000650696,
ENST00000651467,
ENST00000651516,
ENST00000239007,
ENST00000651495,
ENST00000650900
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000498306,
ENSP00000498396,
ENSP00000499161,
ENSP00000498554,
ENSP00000498472,
ENSP00000499209,
ENSP00000499158,
ENSP00000498547,
ENSP00000498928,
ENSP00000498573,
ENSP00000498971,
ENSP00000499128,
ENSP00000358625,
ENSP00000498764,
ENSP00000239007,
ENSP00000354606,
ENSP00000498873,
ENSP00000499087,
ENSP00000331152,
ENSP00000498900,
ENSP00000498390,
ENSP00000498238,
ENSP00000498536
RefSeq:
NP_569157.2,
NP_005953.4,
NP_001008541.1
|
| Others |
UniRef100:
UniRef100_P50539,
UniRef100_A0A2I3HEJ8
UniRef90:
UniRef90_P50539,
UniRef90_P50539-3
UniRef50:
UniRef50_P50539-3,
UniRef50_P50539
UniGene:
Hs.602078,
Hs.728542
CCDS:
CCDS7564.2,
CCDS7563.1,
CCDS31284.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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