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45380 spin

45380

spin

spinster

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition spinster

研究结论

Date Results Publications
2011-07-30 10:43:00 Within the migrating perineurial glial cells, Spinster is required to downregulate Decapentaplegic signaling activity, which ceases migratory abilities. Also, Spinster affects the growth of the carpet cell, which indirectly modulates glial migration. 21562262
2011-07-16 11:30:00 Spinster (Spin) encodes a putative lysosomal efflux permease with the hallmarks of a sugar transporter. Spin mutants accumulate lysosomal carbohydrates and enlarged lysosomes. 21518918
2010-05-03 11:06:00 spin promotes cell death mechanisms that are regulated negatively by th and emc and positively by atg8a 20091795
2010-01-21 00:00:00 Zebrafish yolk-specific not really started (nrs) gene is a vertebrate homolog of the Drosophila spinster gene and is essential for embryogenesis. 11836794
2010-01-21 00:00:00 Spin is expressed in nerve and muscle and is required for normal synaptic growth. Spin is found in a late endosomal compartment;there is evidence for altered endosomal/lysosomal function in Spin-deficient flies. 12408844

名称对应

Type IDs
Synonymous 25/11, CG8428, Dmel\CG8428, Spin, bnch, l(2)10403, l(2)W5, l(2)k02511, l(2)k09905, l(2R)W5
Gene
UniProtKB-ID: SPIN_DROME, R4NR58_DROME
UniprotKB: Q9GQQ0, R4NR58
UniParc: UPI000007A504, UPI0000038C7F, UPI000007A44F, UPI000007EDD0, UPI0000038C80
EMBL: AF212370, AE013599, AF212367, BT150099, AF212368, AF212366, AY051792, BT032842, AF212369
EnsemblGenome: FBgn0086676
KO: dme:Dmel_CG8428
Nucleutide sequences
EMBL-CDS: AAG43828.1, AAF58060.2, AAM70953.1, AAG43825.1, AAM70950.1, AAK93216.1, AAG43826.1, AAG43829.1, AAM70951.1, AAG43827.1, AAM70952.1, ACD81856.1, AGL46748.1
Gene_ORFName: CG8428
EnsemblGenome_TRS: FBtr0089589, FBtr0089593, FBtr0089592, FBtr0089590, FBtr0089591, FBtr0089593
Protein sequencees
EnsemblGenome_PRO: FBpp0088548, FBpp0088551, FBpp0088552, FBpp0088550, FBpp0088549, FBpp0088552
RefSeq: NP_725530.1, NP_725533.1, NP_524823.1, NP_725532.1, NP_725531.1
Others
UniRef100: UniRef100_Q9GQQ0
UniRef90: UniRef90_Q9GQQ0
UniRef50: UniRef50_Q9GQQ0
UniGene: Dm.3446

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