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4507 MTAP

4507

MTAP

methylthioadenosine phosphorylase

protein-coding

Homo sapiens

基因描述

Type Description
Definition methylthioadenosine phosphorylase

研究结论

Date Results Publications
2021-02-20 13:28:00 Loss of 5'-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness. 32093414
2021-02-02 13:23:00 MTAP immunohistochemistry is an accurate and reproducible surrogate for CDKN2A fluorescence in situ hybridization in diagnosis of malignant pleural mesothelioma. 31231127
2020-12-05 13:04:00 MTAP-deficiency could predict better treatment response in advanced lung adenocarcinoma patients initially treated with pemetrexed-platinum chemotherapy and bevacizumab. 31965001
2020-07-11 10:39:00 Authors identified significant associations for rs869330 (in the methylthioadenosine phosphorylase - MTAP gene) with overall survival (hazard ratio = 0.760, P = 0.048, 95% confidence interval: 0.580-0.998) and relapse-free survival (hazard ratio = 0.800, P = 0.020, 95% confidence interval: 0.650-0.970). 30681428
2020-04-11 10:58:00 Loss of MTAP expression is associated with stemness in Glioblastoma. 31040154

名称对应

Type IDs
Synonymous BDMF, DMSFH, DMSMFH, HEL-249, LGMBF, MSAP, c86fus
Gene
UniProtKB-ID: MTAP_HUMAN, A0A384ME80_HUMAN
UniprotKB: Q13126, A0A384ME80
UniParc: UPI00025D0183, UPI00025D0185, UPI000189229B, UPI00025D0182, UPI00025D0181, UPI0000110BBE, UPI00025D0184
EMBL: CH471071, HE654777, AY712791, BC026106, HE654775, L42628, L40432, U22233, L42633, HE654774, HE654772, L42629, L42630, HE654776, L42627, GQ891397, L42631, AL359922, HE654773, L42634, L42632
Ensembl: ENSG00000099810
KO: hsa:4507
Nucleutide sequences
EMBL-CDS: AAA81646.1, AAU04442.1, AAH26106.1, AAR24607.2, CCF77346.1, CCF77345.1, CCF77348.1, CCF77349.1, AAG38871.1, CCF77350.1, CCF77347.1, EAW58606.1, ADO22259.1
Ensembl_TRS: ENST00000644715, ENST00000580900
Protein sequencees
Ensembl_PRO: ENSP00000463424, ENSP00000494373
RefSeq: NP_002442.2
Others
UniRef100: UniRef100_Q13126
UniRef90: UniRef90_Q13126
UniRef50: UniRef50_Q13126
UniGene: Hs.193268
CCDS: CCDS6509.1

全选

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