| Type | Description |
|---|---|
| Definition | lymphocyte antigen 96 |
| Date | Results | Publications |
|---|---|---|
| 2018-03-31 12:06:00 | MD2 is essential to obesity-related cardiac hypertrophy through activating JNK/ERK and NF-kappaB-dependent cardiac inflammatory pathways. Targeting MD2 would be a therapeutic approach to prevent obesity-induced cardiac injury and remodeling. | 28965884 |
| 2015-11-21 10:22:00 | Up-regulation of MD-2 in alveolar macrophages was attenuated after PAI-1 gene knockdown. | 25342286 |
| 2013-09-21 10:06:00 | Data show that rifampin binds to myeloid differentiation protein 2 (MD-2), the key coreceptor for innate immune TLR4. | 23568774 |
| 2012-04-14 11:49:00 | LPS induced increases in TNF-alpha, IL-1 beta and IL-6 protein levels in NR8383 cell supernatants was significantly inhibited by MD-2 silencing. | 21849156 |
| 2011-12-17 11:10:00 | Higher dose LPS can up-regulate the gene expression of TLR4 and MD-2 in rat alveolar macrophage NR8383 cell line, and promote the secretion of TNF-alpha, IL-6 and IL-1beta. | 20646617 |
| Type | IDs |
|---|---|
| Synonymous | MD-2, MD2 |
| Gene |
UniProtKB-ID:
Q56DL5_RAT
UniprotKB:
Q56DL5
UniParc:
UPI00005001DB
EMBL:
AY963291
KO:
rno:448830
|
| Nucleutide sequences |
EMBL-CDS:
AAX73194.1
|
| Protein sequencees |
RefSeq:
XP_017458436.1,
NP_001019450.1,
XP_017449162.1
|
| Others |
UniRef100:
UniRef100_Q56DL5
UniRef90:
UniRef90_Q56DL5
UniRef50:
UniRef50_Q9Y6Y9
UniGene:
Rn.141496
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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