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4485 MST1

4485

MST1

macrophage stimulating 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition macrophage stimulating 1

研究结论

Date Results Publications
2020-09-12 15:58:00 Comparative characterization of the HGF/Met and MSP/Ron systems in primary pancreatic adenocarcinoma. 31254927
2019-11-02 11:12:00 Our analysis suggests that MST1 might interact with key susceptibility genes involved in autophagy and bacterial recognition. These findings provide insight into the genetic architecture of Crohn's disease in Chinese and may partially explain the disparity of genetic signals in Crohn's disease susceptibility across different ethnic populations by highlighting the contribution of gene-gene interactions. 29441677
2019-08-31 12:54:00 Mst1 overexpression inhibits mitophagy activity via suppressing the ERK-Mfn2 pathway, ultimately augmenting IL-24-inducd esophageal cancer death via enhanced mitochondrial stress. 30981108
2019-04-06 11:03:00 Legionella pneumophila effector protein LegK7(lpg1924) hijacks the conserved Hippo signaling pathway by molecularly mimicking host Hippo kinase (MST1 in mammals), which is the key regulator of pathway activation. 30212651
2018-06-01 09:53:00 Mst1 has an important role in inhibiting the growth of NSCLC in vitro and in vivo; its antiproliferative effect is associated with induction of apoptosis. 23928732

名称对应

Type IDs
Synonymous D3F15S2, DNF15S2, HGFL, MSP, NF15S2
Gene
UniProtKB-ID: HGFL_HUMAN, Q53GN8_HUMAN, G3XAK1_HUMAN
UniprotKB: P26927, Q53GN8, G3XAK1
UniParc: UPI000050A7F5, UPI0000EE2A31, UPI000004E6AD
EMBL: AK222893, U37055, CH471055, L11924, M74178, BC048330, AC099668
Ensembl: ENSG00000173531
KO: hsa:4485
Nucleutide sequences
EMBL-CDS: AAA59872.1, AAC50471.1, AAH48330.1, AAA50165.1, BAD96613.1, EAW65000.1
Gene_ORFName: hCG_2001992
Ensembl_TRS: ENST00000383728, ENST00000449682
Protein sequencees
Ensembl_PRO: ENSP00000373234, ENSP00000414287
RefSeq: XP_006713229.1, XP_011532034.1, NP_066278.3, XP_016861953.1, XP_016861957.1, XP_016861950.1, XP_016861955.1, XP_016861951.1, XP_016861952.1, XP_016861954.1, XP_016861949.1, XP_011532040.1, XP_016861956.1
Others
UniRef100: UniRef100_P26927, UniRef100_Q53GN8
UniRef90: UniRef90_P26927
UniRef50: UniRef50_P26927
UniGene: Hs.349110, Hs.512587

全选

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