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4481 MSR1

4481

MSR1

macrophage scavenger receptor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition macrophage scavenger receptor 1

研究结论

Date Results Publications
2021-01-23 13:00:00 Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1. 31972266
2020-10-10 12:57:00 Clinical and transcriptional signatures of human CD204 reveal an applicable marker for the protumor phenotype of tumor-associated macrophages in breast cancer. 31799941
2020-01-18 11:36:00 SRA stimulation lead to selective ERK phosphorylation, which upregulated cytosol reactive oxygen species levels and induced canonical neutrophil extracellular traps formation by activating NADPH oxidase 2 (NOX2). 30850160
2020-01-11 10:58:00 MSR1 K63 polyubiquitylation correlated with the activation of JNK signalling in ovarian cancer tissue from human patients, suggesting that it may be relevant for macrophage phenotypic shift in vivo. MSR1 signals through JNK via K63 polyubiquitylation and is involved in macrophage polarization. 31028084
2019-07-20 11:39:00 identified SR-AI as a novel macrophage-specific receptor for von Willebrand factor. Enhanced binding of von Willebrand factor mutants to SR-AI may contribute to the increased clearance of these mutants. 29326120

名称对应

Type IDs
Synonymous CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII, SRA, phSR1, phSR2
Gene
UniProtKB-ID: MSRE_HUMAN
UniprotKB: P21757
UniParc: UPI000002AE63, UPI00000719D5, UPI000012F686
EMBL: BC063878, DQ144993, D90187, AF037351, D90188, AC023396, D13263, CH471080
Ensembl: ENSG00000038945
KO: hsa:4481
Nucleutide sequences
EMBL-CDS: AAZ38715.1, EAW63833.1, EAW63832.1, BAA14209.1, BAA14208.1, AAH63878.1, EAW63830.1, AAC09251.1, EAW63834.1
Ensembl_TRS: ENST00000350896, ENST00000355282, ENST00000381998, ENST00000262101
Protein sequencees
Ensembl_PRO: ENSP00000347430, ENSP00000371428, ENSP00000262100, ENSP00000262101
RefSeq: NP_619729.1, XP_024302929.1, NP_001350673.1, NP_002436.1, NP_619730.1
Others
UniRef100: UniRef100_P21757
UniRef90: UniRef90_P21757
UniRef50: UniRef50_P21757
UniGene: Hs.147635
CCDS: CCDS5995.1, CCDS5996.1, CCDS5997.1

全选

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