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44786 nerfin-1

44786

nerfin-1

nervous fingers 1

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition nervous fingers 1

研究结论

Date Results Publications
2020-04-04 10:56:00 In this study, the authors identify Nerfin-1 as a transcriptional repressor that antagonizes the activity of the Sd-Yki complex by binding to the TEA DNA-binding domain of Sd. Consistent with its biochemical function, ectopic expression of Nerfin-1 results in tissue undergrowth in an Sd-dependent manner. 30901309
2019-12-14 11:47:00 Scalloped (Sd) and Nervous fingers-1 (Nerfin-1) transcription factors physically and functionally interact to maintain medulla neuron fate in the Drosophila melanogaster central nervous system. 30404010
2017-12-30 12:01:00 Our data revealed a new link to understand the underlying mechanism for Nerfin-1 turnover in post-translational level, and provided useful insights in animal development and disease treatment by manipulating the activity of Slimb and Nerfin-1. 29154825
2017-09-16 11:04:00 Nerfin-1 represses Notch activity in medulla neurons and prevents them from dedifferentiation. 28242614
2015-03-07 12:20:00 (Nerfin-1) locks neurons into differentiation, preventing their reversion into Neuroblasts 25593306

名称对应

Type IDs
Synonymous CG13906, Dmel\CG13906, Nerfin, Nerfin-1, nerfin
Gene
UniProtKB-ID: Q9V3B8_DROME
UniprotKB: Q9V3B8
UniParc: UPI000000C578
EMBL: BT005200, AF203690, AE014296
EnsemblGenome: FBgn0028999
KO: dme:Dmel_CG13906
Nucleutide sequences
EMBL-CDS: AAF47431.1, AAF22973.1, AAO61757.1
Gene_ORFName: CG13906, Dmel_CG13906
EnsemblGenome_TRS: FBtr0072592
Protein sequencees
EnsemblGenome_PRO: FBpp0072489
RefSeq: NP_524783.1
Others
UniRef100: UniRef100_Q9V3B8
UniRef90: UniRef90_Q9V3B8
UniRef50: UniRef50_Q9V3B8
UniGene: Dm.1818

全选

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研究热度

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